SCHEMBL5483790

SCHEMBL5483790

CC(=O)O[Si](OC(C)=O)(OC(C)=O)C(C)OC(=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479880 0.80
SCHEMBL11851987 0.79 TSHR (0.48) TSHR
SCHEMBL5487746 0.76
SCHEMBL321296 0.74 TSHR (0.33) TSHR
SCHEMBL333538 0.74 TSHR (0.37) TSHR
SCHEMBL826905 0.69 TSHR (0.46) TSHR
SCHEMBL9506405 0.69 TSHR (0.38) TSHR
SCHEMBL11197491 0.69
SCHEMBL3446662 0.68 TSHR (0.36) TSHR
SCHEMBL4306399 0.68 TSHR (0.43) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070266896-A1 Siloxane-Based Coating Material, Optical Article, and Production Method of Siloxane-Based Coating Material TORAY INDUSTRIES, INC. (JP) 2007-11-22 US disclosed
EP-1760126-A1 SILOXANE COATING MATERIAL, OPTICAL ARTICLES AND PROCESS FOR THE PRODUCTION OF SILOXANE COATING MATERIALS TORAY INDUSTRIES, INC. (JP) 2007-03-07 EP disclosed