SCHEMBL9506405

SCHEMBL9506405

C=CC(=O)OC(C)[Si](OC(C)=O)(OC(C)=O)OC(C)=O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1200031 0.80 TSHR (0.41) TSHRALDH1A1
SCHEMBL11851987 0.79 TSHR (0.48) TSHRALDH1A1
SCHEMBL4442043 0.77 TSHR (0.35) TSHR
SCHEMBL2476564 0.76 TSHR (0.41) TSHRALDH1A1
SCHEMBL9637767 0.75 TSHR (0.43) TSHRALDH1A1
SCHEMBL333538 0.74 TSHR (0.37) TSHR
SCHEMBL8461587 0.73 TSHR (0.42) TSHRALDH1A1
SCHEMBL28555596 0.72 TSHR (0.41) TSHRALDH1A1
SCHEMBL27722868 0.72 TSHR (0.38) TSHR
SCHEMBL1467437 0.71 TSHR (0.44) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0355157-B1 ADHESION PROMOTERS FOR THIOLENE ADHESIVE FORMULATIONS LOCTITE CORPORATION (US) 1993-07-28 EP disclosed
US-5028661-A Norbornene compounds, acids and peracids, galvanized steel LOCTITE CORPORATION (US) 1991-07-02 US disclosed
EP-0355157-A1 ADHESION PROMOTERS FOR THIOLENE ADHESIVE FORMULATIONS. LOCTITE CORP (US) 1990-02-28 EP disclosed
WO-1989006666-A1 ADHESION PROMOTERS FOR THIOLENE ADHESIVE FORMULATIONS LOCTITE CORPORATION (US) 1989-07-27 WO disclosed