1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL5484020

C=C(Cl)Cl.C=Cc1ccccc1C

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
TSHR P16473 4/20 0.46
ACHE P22303 2/20 0.38
KDM4E B2RXH2 5/20 0.35
RAB9A P51151 4/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2C19 P33261 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
MEN1 O00255 1/20 0.34
PABPC1 P11940 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 2/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
HPGD P15428 1/20 0.34
HTT P42858 1/20 0.34
NPC1 O15118 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
TTR P02766 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1852841 0.89 ALDH1A1 (0.48) ALDH1A1TSHRACHEKDM4ERAB9A
Methyl Alcohol SCHEMBL10861907 0.89 ALDH1A1 (0.52) ALDH1A1TSHRACHEKDM4ERAB9A
SCHEMBL14887 0.89
SCHEMBL29391686 0.89
SCHEMBL678151 0.89 ALDH1A1 (0.56) ALDH1A1TSHRACHEKDM4ERAB9A
Bromide SCHEMBL27952385 0.87 ALDH1A1 (0.46) ALDH1A1TSHRACHEKDM4ERAB9A
Vinyl Chloride SCHEMBL11058117 0.86 ALDH1A1 (0.50) ALDH1A1TSHRACHEKDM4ERAB9A
SCHEMBL10436179 0.86 ALDH1A1 (0.50) ALDH1A1TSHRACHEKDM4ERAB9A
Hydrochloric Acid SCHEMBL5155095 0.86 ALDH1A1 (0.54) ALDH1A1TSHRACHEKDM4ERAB9A
Benzene SCHEMBL11895034 0.86 TSHR (0.54) ALDH1A1TSHRACHEKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007062198-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECHNOLOGY, INC. (US) 2007-05-31 WO disclosed
EP-0430421-B1 Polyurethane/silicone compositions GENCORP INC (US) 1995-03-29 EP disclosed