SCHEMBL5484085

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30368430	1.00	GRIK1 (0.44)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL5492501	0.88	SLC1A3 (0.40)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL15824131	0.82	ALDH1A1 (0.37)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL15824132	0.82	ALDH1A1 (0.37)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL6231973	0.77	GRIK1 (0.48)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	Homoserine SCHEMBL28042341	0.72	GSR (0.54)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	Homoserine SCHEMBL27743664	0.72	GSR (0.54)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL3235556	0.72	GRIK1 (0.44)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL3235567	0.72	GRIK1 (0.44)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3
	SCHEMBL14813217	0.71	CHRM1 (0.41)	GRIK1GRIK2SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.