SCHEMBL5484141

SCHEMBL5484141

CC(=O)Nc1[c]nccc1F

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.37
ADORA2A P29274 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HSD17B10 Q99714 2/20 0.34
GAA P10253 2/20 0.34
HTT P42858 2/20 0.34
PKM P14618 1/20 0.34
ALOX15 P16050 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NAPRT Q6XQN6 1/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5484403 0.82 ALDH1A1 (0.40) HSD17B10ALDH1A1CYP3A4
SCHEMBL5476614 0.81 HTT (0.44) HTTCA1CA2CA9TSHR
SCHEMBL9450132 0.80 ALDH1A1 (0.40) ADORA3SMN1; SMN2MEN1KMT2AHSD17B10
SCHEMBL2067010 0.79 PTK2 (0.39) SMN1; SMN2POLBHSD17B10GAAHTT
SCHEMBL2067157 0.76 ALDH1A1 (0.41) ADORA3ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL5484147 0.75 ALDH1A1 (0.39) SMN1; SMN2MEN1KMT2APOLBHDAC1
SCHEMBL2066556 0.72 TDP1 (0.44) SMN1; SMN2MEN1KMT2AGAAALDH1A1
SCHEMBL2068054 0.70 F2RL1 (0.31)
SCHEMBL5475468 0.69 SMN1; SMN2 (0.44) ADORA3ADORA2ASMN1; SMN2MEN1KMT2A
SCHEMBL2067008 0.68 KDM4E (0.40) SMN1; SMN2MEN1KMT2APOLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD ADORA3 149/4885ADORA2A 214/4885SMN1; SMN2 4822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.