Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.40 |
| ▸ | POR | P16435 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 2/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21568521 | 0.79 | TDP1 (0.41) | ALDH1A1KMT2AMEN1POLBHSP90AA1 | |
| SCHEMBL6751572 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL3363853 | 0.70 | ALDH1A1 (0.52) | ALDH1A1KMT2AMEN1L3MBTL1TSHR | |
| SCHEMBL1063743 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1POLBHSP90AA1 | |
| SCHEMBL13118928 | 0.67 | TSHR (0.50) | ALDH1A1TSHRTDP1MAPTLMNA | |
| SCHEMBL2105183 | 0.66 | TSHR (0.61) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL17119010 | 0.66 | ALDH1A1 (0.55) | ALDH1A1KMT2AMEN1HSP90AA1L3MBTL1 | |
| SCHEMBL30683694 | 0.65 | ALDH1A1 (0.72) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL8440730 | 0.64 | TSHR (0.58) | ALDH1A1KMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL6378439 | 0.64 | TSHR (0.58) | ALDH1A1KMT2AMEN1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664158-B1 | MICROGELS IN CROSS-LINKABLE, ORGANIC MEDIA | ARLANXEO DEUTSCHLAND GMBH (DE) | 2019-05-01 | — | — | EP | disclosed |
| EP-1399163-B1 | COMPOUNDS, METHODS AND COMPOSITIONS USEFUL FOR THE TREATMENT OF BOVINE VIRAL DIARRHEA VIRUS (BVDV) INFECTION AND HEPATITIS C VIRUS (HCV) INFECTION | UNIV NORTH CAROLINA (US) | 2007-10-10 | — | — | EP | disclosed |
| US-20070232733-A1 | organic, crosslinkable medium and at least one microgel which is not crosslinked by high-energy radiation, processes for its preparation, uses of the compositions, microgel-containing polymers prepared therefrom and shaped articles or coatings produced therefrom. | LANXESS DEUTSCHLAND GMBH (DE) | 2007-10-04 | — | — | US | disclosed |