SCHEMBL5484209

SCHEMBL5484209

C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 2/20 0.72
CTSL P07711 5/20 0.67
CTSB P07858 3/20 0.67
CTSS P25774 1/20 0.67
CTSK P43235 1/20 0.67
TACR1 P25103 2/20 0.65
MME P08473 1/20 0.62
ECE1 P42892 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31397615 1.00 CAPN1 (0.72) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL7281206 1.00 CAPN1 (0.72) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL10967811 1.00 CAPN1 (0.72) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL9088735 1.00 CAPN1 (0.72) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL4504085 0.95 CAPN1 (0.67) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL7313795 0.95 CAPN1 (0.67) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL13355677 0.95 CAPN1 (0.67) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL7204154 0.95 CAPN1 (0.67) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL7316923 0.95 CAPN1 (0.67) CAPN1CTSLCTSBCTSSCTSK
SCHEMBL7322756 0.95 CAPN1 (0.67) CAPN1CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119894535-A Oritastatin derivatives and conjugates thereof 祐方有限公司 2025-04-25 CN claimed
WO-2025067446-A1 ANTIBODY-DRUG CONJUGATE TARGETING TROP2, AND PREPARATION METHOD AND USE THEREFOR 信达生物制药(苏州)有限公司 2025-04-03 WO claimed
CN-119119176-A Camptothecin derivatives 伊缪诺金公司 2024-12-13 CN claimed
CN-113766954-B Camptothecin derivatives 伊缪诺金公司 2024-09-24 CN claimed
CN-117320757-A anti-HER 2 antibody-drug conjugates and uses thereof 祐方有限公司 2023-12-29 CN claimed
WO-1993000427-A2 NEURITE GROWTH REGULATORY FACTORS ERZIEHUNGSDIREKTION OF THE CANTON ZURICH (CH) 1993-01-07 WO claimed
EP-0130679-A2 Alpha amino fluoro ketones ENZYME SYSTEMS PRODUCTS INC. (US) 1985-01-09 EP claimed
CN-121021631-A Ganoderma lucidum wall-broken spore powder antioxidant protein peptide and preparation method thereof 浙江省林业科学研究院 2025-11-28 CN disclosed
CN-119894535-A Oritastatin derivatives and conjugates thereof 祐方有限公司 2025-04-25 CN disclosed
WO-2025067446-A1 ANTIBODY-DRUG CONJUGATE TARGETING TROP2, AND PREPARATION METHOD AND USE THEREFOR 信达生物制药(苏州)有限公司 2025-04-03 WO disclosed
CN-119630428-A EPCAM immunoconjugates and uses thereof 西托姆克斯治疗公司 2025-03-14 CN disclosed
CN-119119176-A Camptothecin derivatives 伊缪诺金公司 2024-12-13 CN disclosed
CN-113766954-B Camptothecin derivatives 伊缪诺金公司 2024-09-24 CN disclosed
EP-0272671-B1 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD (CH) 1994-03-16 EP disclosed
US-5223486-A Modified oligopeptide containing a diazomethyl ketone group or methylsulfonium group UNIVERSITY RESEARCH CORPORATION (US) 1993-06-29 US disclosed
US-5158936-A Treating or prevention of tissue damage, inflammation, bone resporpption and muscular dystrophy SYNTEX (U.S.A.) INC. (US) 1992-10-27 US disclosed
US-5055451-A Prevent tissue damage SYNTEX INC. (US) 1991-10-08 US disclosed
EP-0272671-A2 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD. (CH) 1988-06-29 EP disclosed
US-4518528-A α Amino fluoro ketones MP BIOMEDICALS, LLC 1985-05-21 US disclosed
EP-0130679-A2 Alpha amino fluoro ketones ENZYME SYSTEMS PRODUCTS INC. (US) 1985-01-09 EP disclosed