Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 5/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.62 |
| ▸ | CTSS | P25774 | 2/20 | 0.62 |
| ▸ | CTSK | P43235 | 2/20 | 0.62 |
| ▸ | TACR1 | P25103 | 2/20 | 0.60 |
| ▸ | MME | P08473 | 1/20 | 0.58 |
| ▸ | ECE1 | P42892 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355677 | 1.00 | CAPN1 (0.67) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL5484209 | 0.95 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL10967811 | 0.95 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL9088735 | 0.95 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL7281206 | 0.95 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL31397615 | 0.95 | CAPN1 (0.72) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL5491506 | 0.94 | CASP1 (0.65) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL6371162 | 0.92 | CASP1 (0.61) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL29941426 | 0.92 | CTSL (0.62) | CAPN1CTSLCTSBCTSSCTSK | |
| SCHEMBL10971243 | 0.92 | CAPN1 (0.67) | CAPN1CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644772-B1 | OPIOID PEPTIDES | SOD CONSEILS RECH APPLIC (FR) | 2003-04-02 | — | — | EP | disclosed |
| US-5663295-A | ANALGESIC, ANTIDIARRHEA | BIOMEASURE INC. (US) | 1997-09-02 | — | — | US | disclosed |
| US-4496540-A | Therapeutic compounds | BIOMEASURE, INC. (US) | 1985-01-29 | — | — | US | disclosed |