Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.46 |
| ▸ | HTR1B | P28222 | 3/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473673 | 1.00 | SLC6A4 (0.46) | SLC6A4SLC6A2HTR1BHTR1DKDM4E | |
| SCHEMBL5715049 | 0.90 | SLC6A4 (0.50) | SLC6A4SLC6A2HTR1BHTR1DKDM4E | |
| SCHEMBL28054515 | 0.84 | SLC6A4 (0.46) | SLC6A4SLC6A2HTR1BHTR1DKDM4E | |
| SCHEMBL14542614 | 0.83 | SLC6A4 (0.45) | SLC6A4SLC6A2HTR1BHTR1DKDM4E | |
| SCHEMBL9477676 | 0.81 | MCHR1 (0.51) | SLC6A4SLC6A2HTR1BHTR1DKDM4E | |
| SCHEMBL8536438 | 0.81 | SLC6A4 (0.48) | SLC6A4SLC6A2HTR1BHTR1DKDM4E | |
| SCHEMBL5475476 | 0.81 | SLC6A4 (0.63) | SLC6A4SLC6A2HTR1BHTR1DCYP1A2 | |
| SCHEMBL5475484 | 0.81 | SLC6A4 (0.63) | SLC6A4SLC6A2HTR1BHTR1DCYP1A2 | |
| SCHEMBL5475481 | 0.81 | SLC6A4 (0.63) | SLC6A4SLC6A2HTR1BHTR1DCYP1A2 | |
| Hydrochloric Acid SCHEMBL5476212 | 0.80 | SLC6A4 (0.61) | SLC6A4SLC6A2HTR1BHTR1DCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ADRB3, HTR3C, SLC6A2 | SLC6A4 15/4885SLC6A2 3/4885HTR1B 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.