Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1817755 | 0.79 | POLB (0.59) | IDO1POLBHTTMAPTALDH1A1 | |
| SCHEMBL5492557 | 0.75 | FEN1 (0.31) | — | |
| SCHEMBL5105572 | 0.75 | POLB (0.50) | IDO1POLBHTTMAPTALDH1A1 | |
| SCHEMBL28046347 | 0.72 | HTT (0.42) | IDO1POLBHTTMAPTALDH1A1 | |
| SCHEMBL987475 | 0.71 | IDO1 (0.53) | IDO1HTTMAPTALDH1A1MAPK1 | |
| SCHEMBL5881717 | 0.70 | CDK2 (0.40) | — | |
| SCHEMBL986221 | 0.70 | TDP1 (0.52) | IDO1POLBHTTMAPTALDH1A1 | |
| SCHEMBL6644250 | 0.70 | PRKCQ (0.46) | — | |
| SCHEMBL30122384 | 0.70 | TDP1 (0.52) | IDO1POLBHTTMAPTALDH1A1 | |
| SCHEMBL6152687 | 0.69 | POLB (0.54) | POLBMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |