Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28193624 | 0.78 | POLB (0.54) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL15972100 | 0.75 | ALDH1A1 (0.57) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL6529829 | 0.75 | POLB (0.45) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL31125096 | 0.74 | CTSB (0.54) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL5105572 | 0.74 | POLB (0.50) | POLBKMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL28171036 | 0.73 | LMNA (0.56) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL3180816 | 0.72 | SIGMAR1 (0.44) | POLBKMT2AMAPTALDH1A1CYP1A2 | |
| SCHEMBL1817755 | 0.72 | POLB (0.59) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL29495264 | 0.71 | ALDH1A1 (0.52) | POLBKMT2AMEN1PKMMAPT | |
| SCHEMBL14397720 | 0.71 | KMT2A (0.54) | POLBKMT2AMEN1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218344-B1 | OXIDATION COLORANT STARTING PRODUCTS | HENKEL KGAA (DE) | 2005-08-17 | — | — | EP | disclosed |
| EP-1218344-A2 | OXIDATION COLORANT STARTING PRODUCTS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-07-03 | — | — | EP | disclosed |
| WO-2000076977-A2 | OXIDATION COLORANT STARTING PRODUCTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-12-21 | — | — | WO | disclosed |