Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 12/20 | 0.88 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.88 |
| ▸ | P2RY6 | Q15077 | 12/20 | 0.84 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL716499 | 0.94 | P2RY2 (1.00) | P2RY2P2RY4P2RY6P2RY14 | |
| SCHEMBL14396709 | 0.94 | P2RY2 (1.00) | P2RY2P2RY4P2RY6P2RY14 | |
| SCHEMBL716498 | 0.94 | P2RY2 (1.00) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL76683 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL14976686 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL24414746 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL2778525 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL14406726 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL12671699 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 | |
| Uridine Triphosphate SCHEMBL107380 | 0.85 | P2RY2 (0.94) | P2RY2P2RY4P2RY6P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1793006-A2 | Nucleic acid ligands and improved methods for producing the same | GILEAD SCIENCES, INC. (US) | 2007-06-06 | — | — | EP | disclosed |
| US-6184364-B1 | DEHYDRATING URIDINE TO FORM 2,2'-ANHYDROURIDINE, CONVERTING TO UNPROTECTED 2'-AZIDO-2'-DEOXYURIDINE, IODINATING TO FORM 5-IODO-2'-AZIDO, 2'-DEOXYURIDINE, THEN REDUCING TO 5-IODO, 2'-AMINO-2'-DEOXYURIDINE; SELEX LIGANDS | NEXSTAR PHARMACEUTICALS, INC. | 2001-02-06 | — | — | US | disclosed |
| US-5958691-A | DETECTION OF NUCLEIC ACID LIGANDS WITH MODIFIED NUCLEOTIDE TO TARGET GROUPS, SINGLE STRAND NUCLEIC ACIDS AND PARTITIONING THE NUCLEIC ACIDS, AMPLIFICATION | NEXSTAR PHARMACEUTICALS, INC. (US) | 1999-09-28 | — | — | US | disclosed |
| US-5660985-A | CONTACTING MIXTURE OF MODIFIED SINGLE-STRANDED NUCLEIC ACIDS WITH TARGET MOLECULE, PARTITIONING THOSE WITH INCREASED AFFINITY, AMPLIFYING TO IDENTIFY LIGANDS OF TARGET MOLECULE | NEXSTAR PHARMACEUTICALS, INC. (US) | 1997-08-26 | — | — | US | disclosed |