SCHEMBL5484591

SCHEMBL5484591

O=C(O)C(Cc1ccccc1)Oc1ccccc1

nearest known ligand 0.87

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.87
PPARA Q07869 17/20 0.87

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20553481 0.90 PPARG (1.00) PPARGPPARA
SCHEMBL6556100 0.90 PPARG (0.73) PPARGPPARA
SCHEMBL20553479 0.90 PPARG (1.00) PPARGPPARA
SCHEMBL20553475 0.88 PPARG (1.00) PPARGPPARA
SCHEMBL9818821 0.88 PPARG (0.76) PPARGPPARA
SCHEMBL20553473 0.88 PPARG (1.00) PPARGPPARA
SCHEMBL6713386 0.87 PPARG (1.00) PPARGPPARA
SCHEMBL11059661 0.87 PPARG (0.68) PPARGPPARA
SCHEMBL21068011 0.87 PPARG (1.00) PPARGPPARA
SCHEMBL21068010 0.87 PPARG (1.00) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021021927-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2021-02-04 WO claimed
US-5117038-A HERBICIDAL SUBSTITUTED PHENOXYPHENYLPROPIONIC ACID DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1992-05-26 US claimed
EP-0313908-A2 Halogen-substituted phenoxyphenylpropionic acid derivatives BAYER AG (DE) 1989-05-03 EP claimed
JP-51136644-A None JP disclosed
US-20220304957-A1 ANTI-CANCER COMPOSITIONS AND METHODS OF USE UNIV LOUISIANA STATE (US) 2022-09-29 US disclosed
CN-112316206-B Implants containing resorbable metal materials and methods of making the same 中南大学湘雅三医院 2022-09-02 CN disclosed
CN-112316206-A Implants containing resorbable metallic materials and methods of making same 中南大学湘雅三医院 2021-02-05 CN disclosed
WO-2021021927-A1 COMPOSITIONS AND METHODS FOR TREATING PULMONARY EDEMA OR LUNG INFLAMMATION REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2021-02-04 WO disclosed
CN-112188887-A Methods and compositions for targeted delivery of active agents and immunomodulators to lymph nodes 免疫疫苗技术公司 2021-01-05 CN disclosed
WO-2020146876-A2 ANTI-CANCER COMPOSITIONS AND METHODS OF USE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2020-07-16 WO disclosed
EP-3294718-B1 NEW DIFLUOROKETAMIDE DERIVATIVES HOFFMANN LA ROCHE (CH) 2020-04-29 EP disclosed
EP-0166186-A2 Derivatives of substituted phenoxyphenyl-propionic acid BAYER AG (DE) 1986-01-02 EP disclosed
EP-0166186-A2 Derivatives of substituted phenoxyphenyl-propionic acid BAYER AG (DE) 1986-01-02 EP disclosed
EP-0001064-B1 FLUOROSUBSTITUTED PHENOXYBENZYL-OXYCARBONYLDERIVATIVES, -ALCOHOLS AND -HALIDES, PROCESSES FOR THEIR PREPARATION AND THEIR APPLICATION BAYER AG (DE) 1982-07-07 EP disclosed
EP-0000345-B1 SUBSTITUTED PHENOXYBENZYLOXYCARBONYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INSECTICIDES AND ACARICIDES BAYER AG (DE) 1981-04-01 EP disclosed
US-4242357-A INSECTICIDES, MITICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-12-30 US disclosed
EP-0001064-A2 Fluorosubstituted phenoxybenzyl-oxycarbonylderivatives, -alcohols and -halides, processes for their preparation and their application BAYER AG (DE) 1979-03-21 EP disclosed
EP-0000345-A1 Substituted phenoxybenzyloxycarbonyl derivatives, their preparation and their use as insecticides and acaricides BAYER AG (DE) 1979-01-24 EP disclosed
JP-S51136644-A PROCESS FOR PREPARING META-SUBSTITUTED-PHENOXYPHENYLPROPIONIC ACID DER IVATIVES EISAI CO LTD 1976-11-26 JP disclosed
US-3937700-A Novel 1,2-methylene-17α-acyloxy (or improved hydroxy)-9β, 10α-steroid compounds of the pregnane series, pharmaceutic preparations on the basis of the novel compounds and methods of producing said compounds and preparations U.S. PHILIPS CORPORATION (US) 1976-02-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220304957-A1 ANTI-CANCER COMPOSITIONS AND METHODS OF USE H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TP53, MCL1 PPARG 1337/4885PPARA 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.