SCHEMBL21068010

SCHEMBL21068010

CCc1ccc(O[C@@H](Cc2ccccc2)C(=O)O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 1.00
PPARA Q07869 17/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21068011 1.00 PPARG (1.00) PPARGPPARA
SCHEMBL5484591 0.87 PPARG (0.87) PPARGPPARA
SCHEMBL20553481 0.84 PPARG (1.00) PPARGPPARA
SCHEMBL20553479 0.84 PPARG (1.00) PPARGPPARA
SCHEMBL8935920 0.83 PPARG (0.71) PPARGPPARA
SCHEMBL8935911 0.83 PPARG (0.71) PPARGPPARA
SCHEMBL9818821 0.83 PPARG (0.76) PPARGPPARA
SCHEMBL20553473 0.83 PPARG (1.00) PPARGPPARA
SCHEMBL20553475 0.83 PPARG (1.00) PPARGPPARA
SCHEMBL6713386 0.82 PPARG (1.00) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed