SCHEMBL548462

SCHEMBL548462

O=Cc1ccccc1-c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
LMNA P02545 2/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
BACE1 P56817 1/20 0.47
PTPN1 P18031 3/20 0.42
RXRA P19793 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALPL P05186 1/20 0.42
GAA P10253 1/20 0.42
CYP2A6 P11509 1/20 0.41
ERN1 O75460 1/20 0.41
POLB P06746 3/20 0.41
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
XDH P47989 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31177892 1.00 MEN1 (0.48) MEN1KMT2ALMNATHRBBLM
SCHEMBL14236880 0.90 HPRT1 (0.52) MEN1KMT2ALMNATHRBBLM
SCHEMBL1666665 0.86 DNMT1 (0.46) MEN1KMT2ALMNATHRBBLM
SCHEMBL3962387 0.85 ERN1 (0.50) MEN1KMT2ALMNATHRBBLM
SCHEMBL15789565 0.85 MEN1 (0.41) MEN1KMT2ALMNATHRBBLM
SCHEMBL17704125 0.85 MEN1 (0.41) MEN1KMT2ALMNATHRBBLM
SCHEMBL14236988 0.82 KMT2A (0.43) MEN1KMT2ALMNATHRBBLM
SCHEMBL35849993 0.82 MEN1 (0.57) MEN1KMT2ALMNATHRBBLM
SCHEMBL9005 0.82 MEN1 (0.57) MEN1KMT2ALMNATHRBBLM
SCHEMBL249552 0.82 KMT2A (0.71) MEN1KMT2ALMNATHRBBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 291 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115215763-A Mass spectrum matrix material and preparation method thereof 闽江学院 2022-10-21 CN claimed
CN-115058008-A Polysulfone polymer and preparation method thereof 宁夏清研高分子新材料有限公司 2022-09-16 CN claimed
CN-110437143-B Benzyl substituted quinoline and derivative and synthesis method thereof 湘潭大学 2022-08-09 CN claimed
CN-114870881-A Seaweed-derived defective carbon material-supported nickel catalyst and application thereof 青岛大学 2022-08-09 CN claimed
US-20130315834-A1 NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2013-11-28 US claimed
WO-2012039685-A1 A NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-03-29 WO claimed
US-5965591-A MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE SANKYO COMPANY, LIMITED (JP) 1999-10-12 US claimed
EP-0563271-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1993-10-06 EP claimed
WO-1992011295-A1 UV/EB CURABLE BUTYL COPOLYMERS FOR COATING APPLICATIONS EXXON CHEMICAL PATENTS INC. (US) 1992-07-09 WO claimed
US-12552779-B2 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2026-02-17 US disclosed
CN-119504462-A Calix [4] arene cyclohexanediamine derivative and green method for catalyzing asymmetric Aldol reaction by using same 常州大学 2025-02-25 CN disclosed
US-20240358679-A1 PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (KR) 2024-10-31 US disclosed
CN-115058008-B Polysulfone polymer and preparation method thereof 宁夏清研高分子新材料有限公司 2024-01-30 CN disclosed
CN-114082446-B Chiral zirconium catalyst for preparing chiral alpha-hydroxy-beta-keto ester compound and preparation method thereof 南开沧州渤海新区绿色化工研究有限公司 2023-12-22 CN disclosed
EP-0126541-A1 Photopolymerization initiator and method of photopolymerization by use of said initiator NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1984-11-28 EP disclosed
EP-0123842-A1 Photo-curable epoxy resin type composition KABUSHIKI KAISHA TOSHIBA (JP) 1984-11-07 EP disclosed
EP-0114258-A1 Resin encapsulation type photo-semiconductor devices KABUSHIKI KAISHA TOSHIBA (JP) 1984-08-01 EP disclosed
US-4369207-A PHOTOPOLYMERIZING TEIJIN LIMITED (JP) 1983-01-18 US disclosed
US-4254035-A BY REACTING GLYCINE AND AN AROMATIC ALDEHYDE IN THE PRESENCE OF ACETIC ANHYDRIDE DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) 1981-03-03 US disclosed
EP-0015441-A2 Laminated film structure of aromatic polyester and process for production thereof TEIJIN LIMITED (JP) 1980-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552779-B2 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and derivative thereof, preparation method therefor, and composition comprising same for preventing, alleviating or treating neurodegenerative diseases SNCA, HTT, PSEN1 MEN1 1548/4885KMT2A 2385/4885LMNA 1447/4885
US-20130315834-A1 NANOPROBE COMPRISING GOLD COLLOID NANOPARTICLES FOR MULTIMODALITY OPTICAL IMAGING OF CANCER AND TARGETED DRUG DELIVERY FOR CANCER CD47, ALB, HCCS MEN1 2235/4885KMT2A 4160/4885LMNA 4204/4885
US-20240358679-A1 PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES GPX4, GPX1, SELENOI MEN1 3057/4885KMT2A 3162/4885LMNA 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.