SCHEMBL5484653

SCHEMBL5484653

CC(CS(=O)(=O)Br)NC(=O)OCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.54
CA12 O43570 2/20 0.54
CA1 P00915 2/20 0.54
CA9 Q16790 2/20 0.54
ATM Q13315 1/20 0.53
CTSK P43235 4/20 0.51
CTRB1 P17538 2/20 0.50
ELANE P08246 1/20 0.50
CA5A P35218 1/20 0.49
CTSS P25774 4/20 0.49
CTSL P07711 3/20 0.49
CTSB P07858 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3805426 0.87 CA2 (0.55) CA2CA12CA1CA9ATM
SCHEMBL6841173 0.87 CA1 (0.58) CA2CA12CA1CA9ATM
SCHEMBL30630026 0.87 CA1 (0.58) CA2CA12CA1CA9ATM
SCHEMBL30629995 0.86 CA2 (0.54) CA2CA12CA1CA9ATM
SCHEMBL19136379 0.86 CA2 (0.54) CA2CA12CA1CA9ATM
SCHEMBL31089911 0.86 CA2 (0.54) CA2CA12CA1CA9ATM
SCHEMBL5491418 0.83 ATM (0.53) CA2CA12CA1CA9ATM
SCHEMBL6358961 0.82 ATM (0.58) CA2CA12CA1CA9ATM
SCHEMBL19136501 0.81 ATM (0.49) CA2CA12CA1CA9ATM
SCHEMBL13534727 0.81 NPC1 (0.65) ATMCTSKCTRB1ELANECTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1310882-C Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO LTD (JP) 2007-04-18 CN disclosed
US-7161032-B2 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2007-01-09 US disclosed
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2006-07-27 US disclosed
CN-1692098-A Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO LTD (JP) 2005-11-02 CN disclosed
EP-1544193-A1 SULFONAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2005-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof CBR3, CNPY2, STS CA2 348/4885CA12 1795/4885CA1 982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.