Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658600 | 0.94 | THRB (0.43) | HTTTHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL13750530 | 0.94 | THRB (0.43) | HTTTHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL8656526 | 0.91 | NR5A1 (0.46) | HTTTHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL8408794 | 0.91 | HTT (0.39) | HTTALDH1A1KMT2AMAPTHPGD | |
| SCHEMBL8408754 | 0.91 | HTT (0.39) | HTTTHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL3138415 | 0.88 | HTT (0.37) | HTTMAPTHPGDL3MBTL1KDM4E | |
| SCHEMBL8659377 | 0.88 | HTT (0.43) | HTTSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL13810350 | 0.87 | HPGD (0.38) | HTTSMN1; SMN2S1PR2S1PR1S1PR3 | |
| SCHEMBL13750519 | 0.87 | KDM4E (0.40) | HTTTHRBSMN1; SMN2S1PR2S1PR1 | |
| SCHEMBL8666882 | 0.86 | HTT (0.36) | HTTSMN1; SMN2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1755613-A2 | SUBSTITUTED CYCLIC UREA DERIVATIVES | Bayer CropScience AG (DE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005112941-A2 | SUBSTITUTED CYCLIC UREA DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2005-12-01 | — | — | WO | disclosed |