Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634787 | 0.85 | PAOX (0.34) | PAOXALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL28640747 | 0.74 | PAOX (0.39) | PAOXALDH1A1POLBMAPTAPEX1 | |
| SCHEMBL2010622 | 0.74 | PAOX (0.46) | PAOXALDH1A1POLBMAPT | |
| Hydrochloric Acid SCHEMBL2010036 | 0.72 | PAOX (0.44) | PAOXALDH1A1POLBMAPT | |
| SCHEMBL8406301 | 0.71 | CARM1 (0.45) | — | |
| SCHEMBL7905340 | 0.71 | TSHR (0.44) | — | |
| SCHEMBL23344402 | 0.70 | — | — | |
| SCHEMBL12602739 | 0.70 | PAOX (0.59) | PAOXALDH1A1POLBMAPT | |
| SCHEMBL31466454 | 0.69 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL13495508 | 0.68 | SMN1; SMN2 (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753727-A1 | NOVEL CIS-IMIDAZOLINES | F.HOFFMANN-LA ROCHE AG (CH) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005110996-A1 | NOVEL CIS-IMIDAZOLINES | F.HOFFMANN-LA ROCHE AG (CH) | 2005-11-24 | — | — | WO | disclosed |