⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL1363 | 1.00 | — | — | |
| Methylpiperazine SCHEMBL12678259 | 1.00 | — | — | |
| SCHEMBL154155 | 1.00 | PHGDH (0.41) | — | |
| Methylpiperazine SCHEMBL12678252 | 1.00 | — | — | |
| Methylpiperazine SCHEMBL12678256 | 1.00 | — | — | |
| Methylpiperazine SCHEMBL7802072 | 0.96 | — | — | |
| Methylpiperazine SCHEMBL14057910 | 0.96 | — | — | |
| Methylpiperazine SCHEMBL1433029 | 0.96 | — | — | |
| SCHEMBL1044666 | 0.96 | PHGDH (0.45) | — | |
| Methylpiperazine SCHEMBL11062667 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 9295 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324842-A | Dexamethasone weak alkaline derivative and preparation and application of preparation thereof | 沈阳药科大学 | 2024-07-12 | — | — | CN | claimed |
| CN-116410158-B | N-methyl tertiary amine selectivity C (sp3) Process for preparing tetra-substituted diene compounds by H functionalization | 青岛科技大学 | 2024-06-21 | — | — | CN | claimed |
| US-20240199632-A1 | BRIARANE COMPOUNDS AND USE THEIR USE | NATIONAL HEALTH RES INST (TW) | 2024-06-20 | — | — | US | claimed |
| CN-118164980-A | Thiazole orange derivative, preparation method and application thereof | 国科温州研究院(温州生物材料与工程研究所) | 2024-06-11 | — | — | CN | claimed |
| CN-118146165-A | 2,3, 5-Trisubstituted pyrazine compound and preparation method and application thereof | 郑州大学 | 2024-06-07 | — | — | CN | claimed |
| CN-118125997-A | Pterocarpus stilbene paeonol chalcone amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-06-04 | — | — | CN | claimed |
| CN-118084902-A | 2-Aminothiazole pyrimidopyridone compound or pharmaceutically acceptable salt or stereoisomer, preparation method and application | 赣南师范大学 | 2024-05-28 | — | — | CN | claimed |
| CN-118084932-A | Celastracene compound and use thereof | 台湾卫生研究院 | 2024-05-28 | — | — | CN | claimed |
| US-11992499-B2 | Quinoline derivatives for use in the treatment of inflammation diseases | ABIVAX (FR) | 2024-05-28 | — | — | US | claimed |
| CN-118026948-A | Tri-aromatic ring compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-14 | — | — | CN | claimed |
| US-3997540-A | ANTIDEPRESSANT | BURROUGHS WELLCOME CO. (US) | 1976-12-14 | — | — | US | claimed |
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |
| US-3992374-A | TRICHOMONAS PARASITICIDE | SCHERING AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | claimed |
| US-3983117-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | claimed |
| US-3974123-A | Dyes for thermoplastics | BASF AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | claimed |
| US-3957779-A | ANTIMICROBIAL AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | claimed |
| US-3957761-A | Process for the production of 1-aminomethyl-6-phenyl-4h-s-triazolo-[4,3-a][1]benzodiazepines and intermediates | THE UPJOHN COMPANY (US) | 1976-05-18 | — | — | US | claimed |
| US-3956297-A | 9H-Dibenzo[b,f]imidazo[1,2-d][1,4]diazepines | THE UPJOHN COMPANY (US) | 1976-05-11 | — | — | US | claimed |
| US-3947417-A | Triazolobenzodiazepine derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1976-03-30 | — | — | US | claimed |
| US-3933816-A | 3-(Substituted aminomethyl)-7-substituted-3,5-dihydro-as-triazino[4,3-a][1,5]benzodiazepines | THE UPJOHN COMPANY (US) | 1976-01-20 | — | — | US | claimed |