SCHEMBL154155

SCHEMBL154155

CN1CCNCCN(C)CCNCC1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHGDH O43175 1/20 0.41
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
MAPT P10636 1/20 0.36
PDE4A P27815 1/20 0.36
KDR P35968 1/20 0.36
ADRB1 P08588 3/20 0.35
CXCR4 P61073 2/20 0.35
SOS1 Q07889 1/20 0.35
SOS2 Q07890 1/20 0.35
CA2 P00918 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA9 Q16790 1/20 0.33
CHKA P35790 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HTR3E A5X5Y0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methylpiperazine SCHEMBL1363 1.00
Methylpiperazine SCHEMBL54849 1.00
Methylpiperazine SCHEMBL12678259 1.00
Methylpiperazine SCHEMBL12678252 1.00
Methylpiperazine SCHEMBL12678256 1.00
Methylpiperazine SCHEMBL7802072 0.96
Methylpiperazine SCHEMBL14057910 0.96
Methylpiperazine SCHEMBL1433029 0.96
SCHEMBL1044666 0.96 PHGDH (0.45) PHGDHPOLBSMN1; SMN2HIF1AMAPT
Methylpiperazine SCHEMBL11062667 0.96

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2673349-B1 USE OF TRANSITION METAL COMPLEXES AS BLEACH CATALYSTS IN WASHING AND CLEANING COMPOSITIONS WEYLCHEM SWITZERLAND AG (CH) 2015-05-13 EP claimed
US-20140005091-A1 Use of Transition Metal Complexes as Bleach Catalysts in Washing and Cleaning Compositions CLARIANT INTERNATIONAL LTD. (CH) 2014-01-02 US claimed
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2026-03-26 US disclosed
EP-3426760-B1 MANGANESE BLEACH CATALYST GRANULES NOVOZYMES AS (DK) 2023-08-30 EP disclosed
CN-107683326-B Manganese bleach catalyst/enzyme particles for dishwashing detergents 诺维信公司 2021-10-08 CN disclosed
CN-109153943-B Manganese bleach catalyst particles 诺维信公司 2021-08-24 CN disclosed
US-20210179606-A1 COMPOSITIONS COMPRISING MACROCYCLE DERIVATIVES INCORPORATING BRIDGED MACROCYCLES AND METHODS OF PRODUCING AND USING SAME SOUTHWESTERN OKLAHOMA STATE UNIV (US) 2021-06-17 US disclosed
US-11021681-B2 Manganese bleach catalyst granules for use in dishwash detergents NOVOZYMES A/S (DK) 2021-06-01 US disclosed
EP-3625319-B1 COATED GRANULES, USE THEREOF, AND WASHING AND CLEANING AGENTS CONTAINING SAME WEYLCHEM WIESBADEN GMBH (DE) 2021-04-21 EP disclosed
EP-3292192-B1 MANGANESE BLEACH CATALYST / ENZYME GRANULES FOR USE IN DISHWASH DETERGENTS NOVOZYMES AS (DK) 2020-04-08 EP disclosed
CN-110678536-A Coated particles, use thereof and washing and cleaning agents containing same 韦尔化学威斯巴登有限公司 2020-01-10 CN disclosed
US-6387862-B2 LAUNDERING, CLEANING COMPOUND THE PROCTER & GAMBLE COMPANY 2002-05-14 US disclosed
US-20020004473-A1 Bleach compositions THE PROCTER & GAMBLE COMPANY 2002-01-10 US disclosed
US-20010044401-A1 Bleach compositions containing metal bleach catalyst, and bleach activators and/or organic percarboxylic acids THE PROCTER & GAMBLE COMPANY 2001-11-22 US disclosed
US-6306812-B1 TRANSITION METAL COMPLEX OF CROSS-BRIDGED MACROPOLYCYCLIC LIGAND; LAUNDRY DETERGENTS, CLEANING COMPOUNDS PROCTER & GAMBLE COMPANY, THE 2001-10-23 US disclosed
US-6218351-B1 LAUNDRY DETERGENTS; AUTOMATIC DISHWASHING DETERGENT ADDITIVES THE PROCTER & GAMBLE COMPNAY 2001-04-17 US disclosed
EP-0977828-A1 BLEACH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-02-09 EP disclosed
EP-0973855-A1 BLEACH COMPOSITIONS CONTAINING METAL BLEACH CATALYST, AND BLEACH ACTIVATORS AND/OR ORGANIC PERCARBOXYLIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 2000-01-26 EP disclosed
WO-1998039406-A1 BLEACH COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1998-09-11 WO disclosed
WO-1998039405-A1 BLEACH COMPOSITIONS CONTAINING METAL BLEACH CATALYST, AND BLEACH ACTIVATORS AND/OR ORGANIC PERCARBOXYLIC ACIDS THE PROCTER & GAMBLE COMPANY (US) 1998-09-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083865-A1 PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA) LIGANDS AND USE THEREOF KLK3, FOLH1, PSMA1 PHGDH 1070/4885POLB 3628/4885SMN1; SMN2 3130/4885
US-20210179606-A1 COMPOSITIONS COMPRISING MACROCYCLE DERIVATIVES INCORPORATING BRIDGED MACROCYCLES AND METHODS OF PRODUCING AND USING SAME HCCS, CYCS, CYC1 PHGDH 2790/4885POLB 931/4885SMN1; SMN2 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.