SCHEMBL5484988

SCHEMBL5484988

CC(=CCC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
AKR1C3 P42330 1/20 0.42
KMT2A Q03164 2/20 0.41
MAPT P10636 1/20 0.41
FABP5 Q01469 2/20 0.40
FABP7 O15540 1/20 0.40
HTR2A P28223 1/20 0.40
APEX1 P27695 7/20 0.40
ABCB11 O95342 1/20 0.40
LMNA P02545 1/20 0.40
PTGS1 P23219 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14444780 0.76 POLB (0.39) POLBAKR1C3KMT2AFABP5FABP7
SCHEMBL13887078 0.76 POLB (0.39) POLBAKR1C3KMT2AFABP5FABP7
SCHEMBL5482288 0.74 POLB (0.46) POLBAKR1C3KMT2AAPEX1
SCHEMBL5869639 0.74 POLB (0.46) POLBAKR1C3KMT2AAPEX1
Acetic Acid SCHEMBL28553657 0.73 POLB (0.48) POLBKMT2AMAPTFABP5FABP7
SCHEMBL458928 0.72 SLC22A12 (0.39) POLBAKR1C3KMT2AMAPTAPEX1
SCHEMBL616045 0.72 SLC22A12 (0.39) POLBAKR1C3KMT2AMAPTAPEX1
SCHEMBL26180953 0.71 GRIK1 (0.42) POLBMAPTHTR2A
Bicarbonate SCHEMBL29229613 0.71 HTR2A (0.48) POLBKMT2AMAPTFABP5FABP7
SCHEMBL8279094 0.71 POLB (0.50) POLBKMT2AMAPTHTR2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070172772-A1 Microlens OMRON CORPORATION (JP) 2007-07-26 US disclosed