SCHEMBL5482288

SCHEMBL5482288

CC(=CC1c2ccccc2-c2ccccc21)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.46
AKR1C3 P42330 1/20 0.46
APEX1 P27695 8/20 0.42
CYP2C9 P11712 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HDAC9 Q9UKV0 1/20 0.39
HDAC5 Q9UQL6 1/20 0.39
NCOR2 Q9Y618 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5869639 1.00 POLB (0.46) POLBAKR1C3APEX1CYP2C9HDAC3
SCHEMBL18317934 0.82 AKR1C3 (0.41) POLBAKR1C3APEX1CYP2C9KMT2A
SCHEMBL3751216 0.81 HDAC3 (0.41) POLBHDAC3HDAC4HDAC7HDAC8
SCHEMBL31115247 0.81 POLB (0.46) POLBAPEX1HDAC3HDAC4HDAC7
SCHEMBL29194166 0.77 POLB (0.42) POLBAPEX1HDAC3HDAC4HDAC7
SCHEMBL27492862 0.76 POLB (0.41) POLBAPEX1HDAC3HDAC4HDAC7
SCHEMBL28956322 0.74 ALDH1A1 (0.46) POLB
SCHEMBL5484988 0.74 POLB (0.42) POLBAKR1C3APEX1KMT2A
SCHEMBL28588442 0.73 POLB (0.39) POLBKMT2AMEN1CYP1A2TSHR
SCHEMBL29711937 0.71 GPR3 (0.41) POLBHDAC3HDAC4HDAC7HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118852290-B Probe for detecting myrosinase as well as preparation method and application thereof 华东师范大学 2025-02-28 CN claimed
CN-118852290-A Probe for detecting myrosinase as well as preparation method and application thereof 华东师范大学 2024-10-29 CN claimed
EP-3839018-B1 HIGH VISCOSITY INDEX COMB POLYMER VISCOSITY MODIFIERS AND METHODS OF MODIFYING LUBRICANT VISCOSITY USING SAME INFINEUM INT LTD (GB) 2023-10-18 EP claimed
EP-0973636-B1 TRANSPARENT ARTICLE WITH RADIAL REFRACTIVE INDEX GRADIENT AND PROCESS FOR ITS MANUFACTURE ESSILOR INT (FR) 2003-01-02 EP claimed
CN-122079921-A Compound capable of being selectively activated by hypochlorous acid and realizing hydroxyl release, and preparation method and application thereof 2026-05-26 CN disclosed
CN-122055370-A And cyclic nitrogen-containing compound, crystal form thereof, preparation method and application thereof 杭州圣域生物医药科技有限公司 2026-05-15 CN disclosed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN disclosed
CN-120131636-A Twin medicine and composition and application thereof 江苏海洋大学 2025-06-13 CN disclosed
CN-120025292-A Compound with synergistic analgesic effect, pharmaceutical composition, preparation method and application thereof 江苏海洋大学 2025-05-23 CN disclosed
CN-116375645-B Chinese black Ning Zhilei derivative and preparation method and application thereof 好医生药业集团有限公司 2025-04-01 CN disclosed
US-7012123-B2 Acrylic polymer and charge transport material SEKISVI CHEMICAL CO., LTD. (JP) 2006-03-14 US disclosed
EP-1357139-B1 Acrylic polymer and charge transport material SEKISUI CHEMICAL CO LTD (JP) 2004-12-01 EP disclosed
US-20030204036-A1 Acrylic polymer and charge transport material SEKISUI CHEMICAL CO., LTD. 2003-10-30 US disclosed
EP-1357139-A2 Acrylic polymer and charge transport material SEKISUI CHEMICAL CO., LTD. (JP) 2003-10-29 EP disclosed
EP-0699694-B1 Comb polymers ROEHM GMBH (DE) 2000-01-05 EP disclosed
US-5859140-A Method for the production of branched polymerizates ROEHM GMBH CHEMISCHE FABRIK (DE) 1999-01-12 US disclosed
EP-0752427-A2 Polymerisation process for branched polymers RÖHM GMBH (DE) 1997-01-08 EP disclosed
EP-0699694-A2 Comb polymers RÖHM GMBH (DE) 1996-03-06 EP disclosed