SCHEMBL5485043

SCHEMBL5485043

FC(F)(F)C(F)(F)C(F)(F)C(F)(F)c1ccc(CC[Si](Cl)(Cl)Cl)cc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.35
MAOB P27338 1/20 0.32
PTPN2 P17706 1/20 0.31
PTPN1 P18031 1/20 0.31
PTPN6 P29350 1/20 0.31
PTPN11 Q06124 1/20 0.31
CA1 P00915 3/20 0.31
CA2 P00918 3/20 0.31
MIF P14174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5486697 0.98 TAAR1 (0.34) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL5490791 0.98 TAAR1 (0.34) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL21066253 0.80 CA2 (0.43) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL5483410 0.80 TAAR1 (0.55) TAAR1MAOBMIF
SCHEMBL29120822 0.79 CA2 (0.42) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL18242489 0.77 TAAR1 (0.38) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL18378596 0.77 TAAR1 (0.38) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL6848455 0.74 CA2 (0.38) TAAR1MAOBCA2
SCHEMBL18378570 0.74 PTPN2 (0.39) TAAR1MAOBPTPN2PTPN1PTPN6
SCHEMBL18242063 0.74 PTPN2 (0.42) TAAR1MAOBPTPN2PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed