SCHEMBL5485055

SCHEMBL5485055

CC(C)CCOP(=O)(OCCC(C)C)Oc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.46
LAP3 P28838 1/20 0.46
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
PKM P14618 1/20 0.42
SRC P12931 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TDP1 Q9NUW8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15201180 0.97 ANPEP (0.46) ANPEPLAP3MEN1KMT2AL3MBTL1
SCHEMBL9555425 0.88 FDPS (0.42) ANPEPLAP3L3MBTL1PKMTDP1
SCHEMBL2782257 0.87 RARB (0.43) ANPEPLAP3
SCHEMBL6029928 0.87 RARB (0.43) ANPEPLAP3
SCHEMBL206883 0.87 RARB (0.43) ANPEPLAP3
SCHEMBL13230147 0.87 ANPEP (0.44) ANPEPLAP3L3MBTL1PKM
Calcium SCHEMBL8060967 0.86 RARB (0.43) ANPEPLAP3
SCHEMBL9555123 0.85 FDPS (0.42) ANPEPLAP3L3MBTL1PKMTDP1
SCHEMBL9555517 0.85 FDPS (0.42) ANPEPLAP3L3MBTL1PKMTDP1
SCHEMBL574191 0.84 ANPEP (0.42) ANPEPLAP3PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644922-B2 FUNCTIONAL FLUID SOLUTIA INC (US) 2007-06-13 EP disclosed
EP-0823472-B1 Viscosity index improving additives for phosphate ester-containing hydraulic fluids ROHMAX ADDITIVES GMBH (DE) 2004-09-08 EP disclosed
US-RE37101-E1 AIRCRAFT HYDRAULIC FLUIDS SOLUTIA INC. 2001-03-20 US disclosed
US-5863999-A CONTAINING POLYMER COMPRISING AS POLYMERIZED MONOMER UNITS ONE OR MORE ALKYL (METH)ACRYLATES; AIRCRAFT HYDRAULIC FLUIDS ROHM AND HAAS COMPANY (US) 1999-01-26 US disclosed
US-5817606-A ALKYL (METH)ACRYLATE INTERPOLYMERS WITH A MIXTURE OF HIGH, MEDIUM AND LOW MOLECULAR WEIGHT ALKYL GROUPS ROHM AND HAAS COMPANY (US) 1998-10-06 US disclosed
CN-1040018-C Functional fluid MONSANTO CO (US) 1998-09-30 CN disclosed
EP-0644922-B1 FUNCTIONAL FLUID MONSANTO CO (US) 1998-05-13 EP disclosed
EP-0823472-A1 Viscosity index improving additives for phosphate ester-containing hydraulic fluids ROHM AND HAAS COMPANY (US) 1998-02-11 EP disclosed
US-5464551-A Aircraft hydraulic fluid MONSANTO COMPANY (US) 1995-11-07 US disclosed
EP-0644922-A1 FUNCTIONAL FLUID MONSANTO COMPANY (US) 1995-03-29 EP disclosed
CN-1084551-A Functional liquid MONSANTO CO (US) 1994-03-30 CN disclosed
WO-1993025641-A1 FUNCTIONAL FLUID MONSANTO COMPANY (US) 1993-12-23 WO disclosed