Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | THRB | P10828 | 1/20 | 1.00 |
| ▸ | ARG1 | P05089 | 1/20 | 0.53 |
| ▸ | ARG2 | P78540 | 1/20 | 0.53 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ODC1 | P11926 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179812 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL1308931 | 1.00 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL1300539 | 0.87 | ALDH1A1 (0.77) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL9586044 | 0.85 | CYP1A2 (0.74) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL7086649 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL1399007 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL9005565 | 0.84 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL24163861 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL6759254 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2ACYP1A2THRB | |
| SCHEMBL6759253 | 0.81 | MEN1 (0.68) | ALDH1A1MEN1KMT2ACYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170096671-A1 | MICRORNA INDUCTION OF CARDIAC REGENERATION | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2017-04-06 | — | — | US | disclosed |
| US-20170029799-A1 | INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED PROTEIN FRAGMENTS OF TRYPTOPHANYL TRNA SYNTHETASES | PANGU BIOPHARMA LIMITED (HK) | 2017-02-02 | — | — | US | disclosed |
| US-8394939-B2 | Nucleic acid encoding fused | GENENTECH, INC. (US) | 2013-03-12 | — | — | US | disclosed |
| US-7259245-B2 | Anti-fused antibodies | GENENTECH, INC. (US) | 2007-08-21 | — | — | US | disclosed |
| US-20070042415-A1 | ANTI-FUSED ANTIBODIES | GENENTECH, INC. | 2007-02-22 | — | — | US | disclosed |
| US-20070003545-A9 | Interleukin-8 homologous polypeptides and therapeutic uses thereof | EATON DAN L | 2007-01-04 | — | — | US | disclosed |
| US-20050100544-A1 | Interleukin-8 homologous polypeptides and therapeutic uses thereof | GENENTECH, INC. | 2005-05-12 | — | — | US | disclosed |
| US-20040102610-A1 | Anti-fused antibodies | GENENTECH, INC. | 2004-05-27 | — | — | US | disclosed |
| US-6451977-B1 | NUCLEOTIDE SEQUENCE ENCODES ISOLATED FUSED POLYPEPTIDE; VECTORS AND CELLS EXPRESSING IMMUNOADHESINS | GENENTECH, INC. | 2002-09-17 | — | — | US | disclosed |
| CN-1053838-C | Synergism of TNF and IL-4 | RES DEV FOUNDATION (US) | 2000-06-28 | — | — | CN | disclosed |
| EP-0244836-B1 | TRIPEPTIDE DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| CN-1060788-A | Working in coordination with of tumor necrosis factor and interleukin 4 | RES DEV FOUNDATION (US) | 1992-05-06 | — | — | CN | disclosed |
| US-4826814-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0244836-A2 | Tripeptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-11 | — | — | EP | disclosed |
| US-4678800-A | INHIBITORS OF ANGIOTENSIN-CONVERTING ENZYME | CIBA-GEIGY CORPORATION (US) | 1987-07-07 | — | — | US | disclosed |