Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14564256 | 0.87 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL5491022 | 0.83 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL5484038 | 0.77 | PPARD (0.82) | PPARDPPARAPPARG | |
| SCHEMBL14564255 | 0.77 | PPARD (0.66) | PPARDPPARAPPARG | |
| SCHEMBL5489180 | 0.75 | PPARD (0.49) | PPARDPPARAPPARG | |
| SCHEMBL5442942 | 0.74 | PPARD (0.50) | PPARDPPARA | |
| SCHEMBL4808365 | 0.73 | PPARD (0.70) | PPARDPPARAPPARG | |
| SCHEMBL4807067 | 0.73 | PPARD (0.59) | PPARDPPARAPPARG | |
| SCHEMBL10328027 | 0.73 | MAPK1 (0.41) | PPARDPPARA | |
| SCHEMBL14188784 | 0.72 | PPARD (0.49) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | SHIONOGI & CO., LTD. (JP) | 2007-03-08 | — | — | US | disclosed |
| EP-1690538-A1 | ISOXAZOLE DERIVATIVE HAVING AGONISTIC ACTIVITY AGAINST PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR | SHIONOGI & CO., LTD. (JP) | 2006-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054902-A1 | Isoxazole derivatives as peroxisome proliferator-activated receptors agonists | NR1H3, NR1H2, RXRA | PPARD 4/4885PPARA 6/4885PPARG 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.