Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938536 | 0.81 | EPHX1 (0.33) | — | |
| SCHEMBL6720564 | 0.78 | — | — | |
| SCHEMBL7935567 | 0.77 | BCAT2 (0.39) | — | |
| SCHEMBL14842407 | 0.77 | CYP2D6 (0.48) | CYP2D6CYP2C19 | |
| SCHEMBL6728519 | 0.76 | — | — | |
| SCHEMBL10900674 | 0.75 | CYP2D6 (0.58) | CYP2D6CYP2C19 | |
| SCHEMBL25260677 | 0.74 | — | — | |
| SCHEMBL6725151 | 0.74 | — | — | |
| SCHEMBL20838650 | 0.74 | CYP2D6 (0.50) | CYP2D6CYP2C19 | |
| SCHEMBL25213286 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007507447-A | — | — | 2007-03-29 | — | — | JP | claimed |
| EP-1673347-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. Hoffman-la Roche AG (CH) | 2006-06-28 | — | — | EP | claimed |
| WO-2005040126-A1 | SUBSTITUTED DIBENZO-AZEPINE AND BENZO-DIAZEPINE DERIVATIVES USEFUL AS GAMMA-SECRETASE INHIBITORS | F. HOFFMAN-LA ROCHE AG (CH) | 2005-05-06 | — | — | WO | claimed |