Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 10/20 | 0.34 |
| ▸ | CA9 | Q16790 | 10/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 8/20 | 0.33 |
| ▸ | CA2 | P00918 | 8/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738334 | 1.00 | NLRP3 (0.37) | NLRP3CA12CA9MAPTCYP3A4 | |
| SCHEMBL1738333 | 1.00 | NLRP3 (0.37) | NLRP3CA12CA9MAPTCYP3A4 | |
| SCHEMBL12157261 | 0.81 | CA12 (0.36) | CA12CA9TSHRCA1CA2 | |
| SCHEMBL12386266 | 0.78 | CYP3A4 (0.40) | CA12CA9MAPTCYP3A4CYP2C19 | |
| SCHEMBL12386229 | 0.78 | CYP3A4 (0.40) | CA12CA9MAPTCYP3A4CYP2C19 | |
| SCHEMBL254386 | 0.78 | CA12 (0.42) | CA12CA9TSHRCA1CA2 | |
| SCHEMBL11548379 | 0.78 | CA12 (0.42) | CA12CA9TSHRCA1CA2 | |
| SCHEMBL11746006 | 0.78 | CA12 (0.42) | CA12CA9TSHRCA1CA2 | |
| SCHEMBL2290500 | 0.78 | CA12 (0.42) | CA12CA9TSHRCA1CA2 | |
| SCHEMBL11548381 | 0.78 | CA12 (0.42) | CA12CA9TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1754710-A2 | 2'-Fluoroncucleosides | Emory University (US) | 2007-02-21 | — | — | EP | disclosed |