SCHEMBL5485462

SCHEMBL5485462

CNC(=O)CN(Cc1cc(C)c(OC(C)(C)C(=O)O)c(C)c1)Cc1nc(-c2cccc(Cl)c2)oc1C

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.62
PPARG P37231 15/20 0.62
CYP2C9 P11712 1/20 0.42
KCNH2 Q12809 1/20 0.42
MAPT P10636 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5487292 0.92 PPARA (0.72) PPARAPPARG
SCHEMBL5482151 0.92 PPARG (0.52) PPARAPPARGCYP2C9KCNH2MAPT
SCHEMBL5487241 0.91 PPARA (0.62) PPARAPPARG
SCHEMBL5487765 0.88 PPARA (0.64) PPARAPPARG
SCHEMBL5477639 0.86 PPARA (0.64) PPARAPPARG
SCHEMBL5484127 0.85 PPARA (0.60) PPARAPPARG
SCHEMBL5483079 0.85 PPARA (0.71) PPARAPPARG
SCHEMBL5481228 0.84 PPARG (0.56) PPARAPPARGCYP2C9KCNH2
SCHEMBL5483150 0.84 PPARA (0.61) PPARAPPARG
SCHEMBL5478864 0.83 PPARA (0.67) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885CYP2C9 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.