SCHEMBL5484127

SCHEMBL5484127

Cc1cc(CN(C)C(=O)N(C)Cc2nc(-c3cccc(Cl)c3)oc2C)cc(C)c1OC(C)(C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 16/20 0.60
PPARG P37231 15/20 0.60
NR1H2 P55055 2/20 0.44
NR1H3 Q13133 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5482142 0.92 PPARG (0.51) PPARAPPARGNR1H2NR1H3
SCHEMBL5487230 0.90 PPARA (0.61) PPARAPPARG
SCHEMBL5485451 0.87 PPARA (0.54) PPARAPPARG
SCHEMBL5485462 0.85 PPARA (0.62) PPARAPPARG
SCHEMBL5475390 0.82 PPARA (0.51) PPARAPPARG
SCHEMBL5484165 0.82 PPARA (0.85) PPARAPPARG
SCHEMBL5481228 0.80 PPARG (0.56) PPARAPPARGNR1H2NR1H3
SCHEMBL5482138 0.80 PPARA (0.47) PPARAPPARGNR1H2NR1H3
SCHEMBL5485446 0.79 PPARA (0.51) PPARAPPARG
SCHEMBL5471909 0.79 PPARA (0.77) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070281112-A1 Thermoplastic film and method of producing the same, polarizing plate, optical compensation film, antireflection film and liquid-crystal display device FUJIFILM CORPORATION (JP) 2007-12-06 US disclosed