Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ERN1 | O75460 | 4/20 | 0.51 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8380501 | 0.82 | PTPN1 (0.59) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL3391145 | 0.81 | LCK (0.65) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL9618790 | 0.81 | KDM4E (0.55) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL7088722 | 0.80 | PTPN1 (0.64) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL3914003 | 0.80 | KDM4E (0.53) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL4361721 | 0.79 | ESR1 (0.53) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL1434717 | 0.79 | ESR1 (0.53) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL29980349 | 0.79 | ESR1 (0.53) | KDM4EMAPTCA12CA1CA2 | |
| SCHEMBL2748359 | 0.79 | ESR1 (0.53) | KDM4EMAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL3914780 | 0.79 | KDM4E (0.52) | KDM4EMAPTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1783221-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX Corp. (US) | 2007-05-09 | — | — | EP | disclosed |
| US-7001729-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2006-02-21 | — | — | US | disclosed |
| US-6906174-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6906175-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor. | MIGENIX CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| US-6902908-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-06-07 | — | — | US | disclosed |
| US-6887670-B2 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. (US) | 2005-05-03 | — | — | US | disclosed |
| US-20050064530-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-03-24 | — | — | US | disclosed |
| US-20050019835-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-27 | — | — | US | disclosed |
| US-20050003353-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-06 | — | — | US | disclosed |
| US-20050003352-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MIGENIX CORP. | 2005-01-06 | — | — | US | disclosed |
| US-20040241801-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MITOKOR, INC. | 2004-12-02 | — | — | US | disclosed |
| EP-1283884-A2 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MITOKOR (US) | 2003-02-19 | — | — | EP | disclosed |
| US-20020012992-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. | 2002-01-31 | — | — | US | disclosed |
| US-20010044144-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | MIGENIX CORP. | 2001-11-22 | — | — | US | disclosed |
| WO-2000026370-A9 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2001-11-15 | — | — | WO | disclosed |
| WO-2001085944-A2 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | MITOKOR (US) | 2001-11-15 | — | — | WO | disclosed |
| EP-1049780-A1 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2000-11-08 | — | — | EP | disclosed |
| WO-2000026370-A2 | ADENINE NUCLEOTIDE TRANSLOCATOR (ANT) FUSION PROTEINS AND USES THEREOF | MITOKOR (US) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044144-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | GART, TMEM165, SLC43A3 | KDM4E 4803/4885MAPT 4628/4885CA12 4495/4885 |
| US-20050003353-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | KDM4E 4803/4885MAPT 4628/4885CA12 4495/4885 |
| US-20040241801-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | GART, TMEM165, SLC43A3 | KDM4E 4803/4885MAPT 4628/4885CA12 4495/4885 |
| US-20050003352-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | KDM4E 4803/4885MAPT 4628/4885CA12 4495/4885 |
| US-20050064530-A1 | PRODUCTION OF ADENINE NUCLEOTIDE TRANSLOCATOR (ANT), NOVEL ANT LIGANDS AND SCREENING ASSAYS THEREFOR | GART, TMEM165, SLC43A3 | KDM4E 4803/4885MAPT 4628/4885CA12 4495/4885 |
| US-20020012992-A1 | Production of adenine nucleotide translocator (ANT), novel ANT ligands and screening assays therefor | GART, TMEM165, SLC43A3 | KDM4E 4803/4885MAPT 4628/4885CA12 4495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.