Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.67 |
| ▸ | PAM | P19021 | 2/20 | 0.60 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.58 |
| ▸ | PPARG | P37231 | 7/20 | 0.58 |
| ▸ | PPARD | Q03181 | 7/20 | 0.58 |
| ▸ | PPARA | Q07869 | 7/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | TLR2 | O60603 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365683 | 1.00 | DGKA (0.67) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL3503363 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL405153 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL31169670 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL3447290 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL2320735 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| Hexanoate SCHEMBL7022784 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL3503295 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG | |
| Ammonia Solution, Strong SCHEMBL2538451 | 0.98 | DGKA (0.64) | DGKAPAMAKR1B1GPR84PPARG | |
| SCHEMBL3504758 | 0.98 | DGKA (0.70) | DGKAPAMAKR1B1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115322268-A | Butyronitrile soft rubber with high acrylonitrile content and low Mooney force and preparation method thereof | 安庆华兰科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| WO-2007062198-A1 | METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY | ADVANCED CELL TECHNOLOGY, INC. (US) | 2007-05-31 | — | — | WO | disclosed |