Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 10/20 | 0.84 |
| ▸ | ACHE | P22303 | 9/20 | 0.84 |
| ▸ | APP | P05067 | 2/20 | 0.75 |
| ▸ | BACE1 | P56817 | 2/20 | 0.75 |
| ▸ | GABRP | O00591 | 1/20 | 0.75 |
| ▸ | GABRD | O14764 | 1/20 | 0.75 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.75 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.75 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.75 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.75 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.75 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.75 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.75 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.75 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.75 |
| ▸ | GABRE | P78334 | 1/20 | 0.75 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.75 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.75 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.75 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484044 | 0.96 | BCHE (0.79) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL5489226 | 0.95 | ACHE (0.80) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL5486214 | 0.95 | ACHE (0.80) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL5487641 | 0.94 | BCHE (0.74) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL28307694 | 0.92 | BCHE (0.86) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL28307695 | 0.88 | BCHE (0.80) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL24000133 | 0.87 | BCHE (0.97) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL13480729 | 0.87 | BCHE (0.92) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL28307696 | 0.87 | BCHE (0.81) | BCHEACHEAPPBACE1GABRP | |
| SCHEMBL5492085 | 0.86 | BCHE (0.68) | BCHEACHEAPPBACE1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299093-A1 | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation | Alma Mater Studiorum-Universitá Di Bologna (IT) | 2007-12-27 | — | — | US | disclosed |
| US-7307083-B2 | Tetrahydro-acridine and dithiolane derivatives | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2007-12-11 | — | — | US | disclosed |
| US-20070219241-A1 | Organic Compounds Useful For The Treatment Of Alzheimer's Disease, Their Use And Method Of Preparation | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219241-A1 | Organic Compounds Useful For The Treatment Of Alzheimer's Disease, Their Use And Method Of Preparation | OTC, PSEN2, PSEN1 | BCHE 7/4885ACHE 5/4885APP 12/4885 |
| US-20070299093-A1 | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation | OTC, PSEN2, PSEN1 | BCHE 7/4885ACHE 5/4885APP 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.