Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 18/20 | 0.51 |
| ▸ | BRAF | P15056 | 17/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5484353 | 0.92 | RAF1 (0.48) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL4551611 | 0.91 | CSF1R (0.43) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL5487365 | 0.91 | MAPK14 (0.46) | RAF1BRAFMAPK14 | |
| SCHEMBL5490015 | 0.86 | RAF1 (0.52) | RAF1BRAFCSF1R | |
| SCHEMBL4411276 | 0.85 | RAF1 (0.53) | RAF1BRAFCSF1R | |
| SCHEMBL4551612 | 0.84 | RAF1 (0.52) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL4417256 | 0.83 | RAF1 (0.52) | RAF1BRAFCSF1RMAPK14 | |
| SCHEMBL4565880 | 0.82 | MAPK14 (0.44) | RAF1BRAFMAPK14 | |
| SCHEMBL5487782 | 0.81 | RAF1 (0.57) | RAF1BRAFCSF1R | |
| SCHEMBL4409370 | 0.81 | RAF1 (0.51) | RAF1BRAFCSF1RMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056016-A2 | BISAMIDE CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |