SCHEMBL5485747

SCHEMBL5485747

C=C(C)C(=O)OC(CCC[Si](C)(C)C)C(O)CO

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1398246 0.86
SCHEMBL1274033 0.86
SCHEMBL5838348 0.86
SCHEMBL275196 0.83 TSHR (0.41) TSHR
SCHEMBL5486101 0.83
SCHEMBL29754447 0.82 TSHR (0.33) TSHR
SCHEMBL4566106 0.81 TSHR (0.46) TSHR
SCHEMBL30339850 0.80
SCHEMBL8466740 0.80
SCHEMBL8465842 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11866531-B2 Oil-resistant lens material and ophthalmic devices Twenty Twenty Therapeutrics LLC (US) 2024-01-09 US disclosed
WO-2021067189-A1 OIL-RESISTANT LENS MATERIAL AND ELECTROWETTING OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC (US) 2021-04-08 WO disclosed
US-20210095063-A1 OIL-RESISTANT LENS MATERIAL AND OPHTHALMIC DEVICES VERILY LIFE SCIENCES LLC 2021-04-01 US disclosed
US-10752833-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2020-08-25 US disclosed
CN-104024891-B For correcting the optical element of colour blindness 日东电工株式会社 2019-06-28 CN disclosed
US-20190194535-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2019-06-27 US disclosed
EP-1589367-B1 PHOTOCHROMIC CONTACT LENS EXCELLING IN DECOLORING CHARACTERISTIC MENICON CO LTD (JP) 2019-03-13 EP disclosed
US-10119070-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-11-06 US disclosed
US-9885883-B2 Optical element for correcting color blindness NITTO DENKO CORPORATION (JP) 2018-02-06 US disclosed
US-20170088771-A1 OPTICAL ELEMENT FOR CORRECTING COLOR BLINDNESS NITTO DENKO CORPORATION (JP) 2017-03-30 US disclosed
US-7261844-B2 For effectively reducing a period of time for discoloring a contact lens from a colored state to an uncolored state MENICON CO., LTD. (JP) 2007-08-28 US disclosed
US-7037954-B2 Ocular lens material MENICON CO., LTD. (JP) 2006-05-02 US disclosed
EP-1197782-B1 MATERIAL FOR OCULAR LENS MENICON CO LTD (JP) 2004-06-02 EP disclosed
US-20040039077-A1 Ocular lens material MENICON CO., LTD. 2004-02-26 US disclosed
US-6638991-B2 Lens material comprising a copolymer derived from a polysiloxane endcapped with acrylated urethane groups, a silicon-containing alkyl methacrylate, a hydrophilic monomer, and a crosslinking monomer; oxygen permeability, strength MENICON CO., LTD. (JP) 2003-10-28 US disclosed
US-20020198280-A1 Material for ocular lens MENICON CO., LTD. (JP) 2002-12-26 US disclosed
EP-1197782-A1 MATERIAL FOR OCULAR LENS MENICON CO., LTD. (JP) 2002-04-17 EP disclosed
EP-0294515-B1 Contact lens material MENICON CO LTD (JP) 1994-05-25 EP disclosed
US-4814402-A VINYLPYRROLIDONE OR METHACRYLIC ACID AND SILICON CONTAINING METHACRYLATE MENICON CO., LTD. (JP) 1989-03-21 US disclosed
EP-0294515-A2 Contact lens material Menicon Co., Ltd. (JP) 1988-12-14 EP disclosed