Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598819 | 0.83 | CYP2A6 (0.46) | CYP2A6HSD11B1CSNK2A1METAP2SQOR | |
| SCHEMBL29473772 | 0.83 | CYP2A6 (0.46) | CYP2A6HSD11B1CSNK2A1METAP2SQOR | |
| SCHEMBL11317813 | 0.82 | ALDH1A1 (0.39) | HSD11B1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL2140618 | 0.78 | CYP2A6 (0.50) | CYP2A6HSD11B1CSNK2A1METAP2ACLY | |
| SCHEMBL21600237 | 0.76 | CYP2A6 (0.46) | CYP2A6CSNK2A1METAP2ACLYCYP1A2 | |
| SCHEMBL27900205 | 0.75 | CYP2A6 (0.46) | CYP2A6HSD11B1CSNK2A1SQORCYP1A2 | |
| SCHEMBL10715265 | 0.75 | CYP2A6 (0.46) | CYP2A6HSD11B1CSNK2A1SQORCYP1A2 | |
| SCHEMBL29674520 | 0.75 | CYP2A6 (0.46) | CYP2A6HSD11B1CSNK2A1METAP2ACLY | |
| SCHEMBL2810864 | 0.75 | ALDH1A1 (0.52) | CYP2A6ACLYALDH1A1TSHRHSD17B10 | |
| SCHEMBL25369445 | 0.75 | CYP2A6 (0.50) | CYP2A6CSNK2A1METAP2CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7227027-B2 | Carbazole derivative and its use in electroluminescent devices | TSINGHUA UNIVERSITY (CH) | 2007-06-05 | — | — | US | disclosed |
| US-20050127826-A1 | Carbazole derivative and its use in electroluminescent devices | BEIJING VISIONOX TECHNOLOGY CO., LTD. (CN) | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050127826-A1 | Carbazole derivative and its use in electroluminescent devices | OCIAD1, OCIAD2, EED | CYP2A6 3812/4885HSD11B1 1920/4885CSNK2A1 1197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.