SCHEMBL5486169

SCHEMBL5486169

CCc1ccc2c(c1CC)-c1ccccc1-2

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.37
LMNA P02545 3/20 0.37
NPC1 O15118 2/20 0.37
MAPK1 P28482 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP2D6 P10635 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
CSNK2A1 P68400 1/20 0.34
CSNK2A3 Q8NEV1 1/20 0.34
DNMT1 P26358 1/20 0.33
PDK2 Q15119 1/20 0.33
GABRA1 P14867 2/20 0.32
GABRB2 P47870 2/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21875509 0.79 ALDH1A1 (0.32) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL9188745 0.79 SMN1; SMN2 (0.35) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL9188476 0.79 NPC1 (0.37) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL3798382 0.79 MAPK1 (0.50) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL27991553 0.76 KDM4E (0.40) ALDH1A1DNMT1PDK2KDM4EELANE
SCHEMBL7006710 0.76 PDK2 (0.47) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL10783896 0.76 PDK2 (0.47) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL11550615 0.76 PDK2 (0.47) MAPTLMNANPC1MAPK1RAB9A
SCHEMBL30359260 0.73 ANPEP (0.43) MAPTLMNAMAPK1SMN1; SMN2ALDH1A1
SCHEMBL3344679 0.73 ANPEP (0.43) MAPTLMNAMAPK1SMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070012569-A1 Cationic electrodeposition coating composition NIPPON PAINT CO., LTD. (JP) 2007-01-18 US disclosed