Phenol

Phenol

SCHEMBL5486172

Oc1ccccc1.c1ccc(COCc2ccccc2)cc1

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.79
CA1 P00915 5/20 0.58
CA2 P00918 3/20 0.58
CA9 Q16790 3/20 0.58
CA12 O43570 1/20 0.58
GLA P06280 1/20 0.58
CA3 P07451 1/20 0.58
CA4 P22748 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CA14 Q9ULX7 1/20 0.58
LMNA P02545 2/20 0.58
CYP1A2 P05177 1/20 0.58
PTGS1 P23219 1/20 0.58
SLC6A2 P23975 1/20 0.58
CYP2C19 P33261 1/20 0.58
PTGS2 P35354 1/20 0.58
SLC6A3 Q01959 1/20 0.58
HIF1A Q16665 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
KDM4E B2RXH2 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL21518644 1.00 TSHR (0.79) TSHRCA1CA2CA9CA12
Hydroquinone SCHEMBL51561 0.95 TSHR (0.79) TSHRCA1CA2CA9CA12
Phenol SCHEMBL28657771 0.93 TSHR (0.68) TSHRCA1CA2CA9CA12
SCHEMBL1840533 0.92 TSHR (0.75) TSHRCA1CA2CA9CA12
Hydroquinone SCHEMBL7511716 0.92 TSHR (0.75) TSHRCA1CA2CA9CA12
Hydrogen Peroxide SCHEMBL28758135 0.92 TSHR (0.94) TSHRCA1CA2CA9CA12
Phenol SCHEMBL9862153 0.89 TSHR (0.62) TSHRCA1CA2CA9CA12
SCHEMBL27380 0.89 TSHR (1.00) TSHRCA1CA2CA9LMNA
SCHEMBL5311581 0.89 TSHR (1.00) TSHRCA1CA2CA9LMNA
Resorcinol SCHEMBL2944120 0.88 TSHR (0.68) TSHRCA1CA2CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4506103-A Process for the preparation of o-benzylphenol BAYER AKTIENGESELLSCHAFT (DE) 1985-03-19 US claimed
JP-1236222-A None JP disclosed
JP-1236220-A None JP disclosed
JP-1236218-A None JP disclosed
JP-2001420-A None JP disclosed
CN-111093857-B Polyurethane-curable organic binder for casting molds, and molding sand composition and casting mold obtained using same 旭有机材株式会社 2022-04-26 CN disclosed
CN-110461498-B Polyurethane-curable organic binder for casting molds, and molding sand composition and casting mold obtained using same 旭有机材株式会社 2021-10-08 CN disclosed
CN-111093857-A Polyurethane-curable organic binder for casting molds, and molding sand composition and casting mold obtained using same 旭有机材株式会社 2020-05-01 CN disclosed
CN-108384489-A A kind of high-performance glass adhesive tape glue and preparation method thereof 如皋市嘉好热熔胶有限公司 2018-08-10 CN disclosed
CN-100503722-C Method of increasing cold box resin high-temperature behavior SUZHOU XINGYE CASTING MATERIAL (CN) 2009-06-24 CN disclosed
US-4971995-A INHIBITORS OF MONOAMINE OXIDASE, NEUROLOGICAL DISORDERS, AGING, MEMORY PROBLEMS, SCHIZOPHRENIA, PSYDHAESTHINIA, PARKINSON*S DISEASE DELANDE S.A. (FR) 1990-11-20 US disclosed
JP-H021420-A ALKYL OR BENZYL PHENOL ETHER, ITS PREPARATION AND ITS THERAPEUTIC USE DELALANDE SA 1990-01-05 JP disclosed
JP-H01236222-A EXPANDED HEAT-INSULATING MATERIAL MATSUSHITA REFRIG CO LTD 1989-09-21 JP disclosed
JP-H01236220-A EXPANDED HEAT-INSULATING MATERIAL MATSUSHITA REFRIG CO LTD 1989-09-21 JP disclosed
JP-H01236218-A EXPANDED HEAT-INSULATING MATERIAL MATSUSHITA REFRIG CO LTD 1989-09-21 JP disclosed
US-4506103-A Process for the preparation of o-benzylphenol BAYER AKTIENGESELLSCHAFT (DE) 1985-03-19 US disclosed
US-4332942-A 3-(2-Hydroxy-4-(substituted)phenyl)azacycloalkanes as analgesics PFIZER, INC. (US) 1982-06-01 US disclosed
US-4306097-A 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents PFIZER INC. (US) 1981-12-15 US disclosed
US-4039715-A ORGANIC ESTERS, WAXES, PARTIALLY ORIENTED YARN EASTMAN KODAK COMPANY (US) 1977-08-02 US disclosed
US-3951825-A ORGANIC ESTERS EASTMAN KODAK COMPANY (US) 1976-04-20 US disclosed