Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.77 |
| ▸ | ACHE | P22303 | 1/20 | 0.65 |
| ▸ | RAD52 | P43351 | 1/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL491770 | 0.96 | HRH3 (0.82) | HRH3ACHERAD52TSHR | |
| SCHEMBL5858552 | 0.94 | HRH3 (0.80) | HRH3ACHERAD52TSHR | |
| SCHEMBL491935 | 0.93 | HRH3 (0.88) | HRH3ACHERAD52 | |
| SCHEMBL5857787 | 0.91 | HRH3 (0.86) | HRH3ACHERAD52 | |
| Hydrochloric Acid SCHEMBL9061899 | 0.91 | HRH3 (0.86) | HRH3ACHERAD52 | |
| SCHEMBL17308548 | 0.91 | HRH3 (0.85) | HRH3ACHERAD52 | |
| SCHEMBL19043356 | 0.89 | HRH3 (0.76) | HRH3ACHERAD52 | |
| SCHEMBL492409 | 0.89 | HRH3 (0.83) | HRH3ACHERAD52TSHR | |
| SCHEMBL10899705 | 0.88 | HRH3 (0.72) | HRH3TSHR | |
| SCHEMBL10895401 | 0.88 | HRH3 (0.72) | HRH3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863487-A2 | TREATMENT OF PARKINSON'S DISEASE, OBSTRUCTIVE SLEEP APNEA, DEMENTIA WITH LEWY BODIES, VASCULAR DEMENTIA WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS | BIOPROJET (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006103546-A2 | TREATMENT OF PARKINSON'S DISEASE, OBSTRUCTIVE SLEEP APNEA, DEMENTIA WITH LEWY BODIES, VASCULAR DEMENTIA WITH NON-IMIDAZOLE ALKYLAMINES HISTAMINE H3-RECEPTOR LIGANDS | BIOPROJET (FR) | 2006-10-05 | — | — | WO | disclosed |