Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035015 | 0.83 | ALDH1A1 (0.47) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL27618766 | 0.81 | TSHR (0.52) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL7754207 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ALOX15 | |
| SCHEMBL6254588 | 0.81 | ALDH1A1 (0.45) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL2689636 | 0.79 | HTT (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL3044735 | 0.76 | ALDH1A1 (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL9784800 | 0.75 | TSHR (0.50) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6257984 | 0.74 | ALDH1A1 (0.47) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL6257222 | 0.74 | ALDH1A1 (0.47) | MEN1THRBHTTKMT2AMAPT | |
| SCHEMBL20106526 | 0.74 | ALDH1A1 (0.38) | MEN1THRBHTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1849760-A1 | Ether compounds, compositions, and uses thereof | Esperion Therapeutics Inc. (US) | 2007-10-31 | — | — | EP | claimed |