SCHEMBL5486480

SCHEMBL5486480

O=Cc1csc(Cl)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15634913 0.76
SCHEMBL6209646 0.72 CA1 (0.39)
SCHEMBL21622292 0.67 CYP2A6 (0.44)
SCHEMBL28946910 0.66 ALDH1A1 (0.31)
SCHEMBL3194258 0.65
SCHEMBL1177826 0.64
SCHEMBL10413565 0.64 TDP1 (0.52)
SCHEMBL17215391 0.62
SCHEMBL20954493 0.60 CYP2A6 (0.56)
SCHEMBL11111158 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-8202894-B2 Microbiocides SYNGENTA CROP PROTECTION LLC (US) 2012-06-19 US disclosed
US-8202894-B2 Microbiocides SYNGENTA CROP PROTECTION LLC (US) 2012-06-19 US disclosed
US-20100227898-A1 NOVEL MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-09-09 US disclosed
US-20100227898-A1 NOVEL MICROBIOCIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-09-09 US disclosed
WO-2009003672-A2 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2009-01-08 WO disclosed
US-7307174-B2 Process and intermediates for the preparation of thienopyrrole derivatives ASTRAZENECA AB (SE) 2007-12-11 US disclosed
US-7307174-B2 Process and intermediates for the preparation of thienopyrrole derivatives ASTRAZENECA AB (SE) 2007-12-11 US disclosed
US-7307174-B2 Process and intermediates for the preparation of thienopyrrole derivatives ASTRAZENECA AB (SE) 2007-12-11 US disclosed
US-20050272938-A1 Process and intermediates for the preparation of thienopyrrole derivatives ASTRAZENECA AB (SE) 2005-12-08 US disclosed
EP-1549653-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF THIENOPYRROLE DERIVATIVES Astrazeneca AB (SE) 2005-07-06 EP disclosed
WO-2004031193-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF THIENOPYRROLE DERIVATIVES ASTRAZENECA AB (SE) 2004-04-15 WO disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed
EP-0008361-B1 HALOGEN-SUBSTITUTED THIOPHENE DERIVATIVES AND METHOD FOR THEIR PREPARATION BASF Aktiengesellschaft (DE) 1982-01-27 EP disclosed
US-4288449-A DIURETICS BASF AKTIENGESELLSCHAFT (DE) 1981-09-08 US disclosed
EP-0007544-B1 THIENYL-DITHIOPHOSPHORIC ACID ESTERS, PROCESS FOR THEIR PREPARATION, THEIR USE AS PESTICIDES, PROCESS FOR THEIR PREPARATION AND METHOD FOR COMBATING PESTS BASF Aktiengesellschaft (DE) 1981-09-02 EP disclosed
US-4268506-A PESTICIDES BASF AKTIENGESELLSCHAFT (US) 1981-05-19 US disclosed
EP-0008367-A1 N-Arylsulfonyl pyrroles, their preparation and medicaments containing them BASF Aktiengesellschaft (DE) 1980-03-05 EP disclosed
EP-0008361-A1 Halogen-substituted thiophene derivatives and method for their preparation BASF Aktiengesellschaft (DE) 1980-03-05 EP disclosed
EP-0007544-A1 Thienyl-dithiophosphoric acid esters, process for their preparation, their use as pesticides, process for their preparation and method for combating pests BASF Aktiengesellschaft (DE) 1980-02-06 EP disclosed