Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 9/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CDA | P32320 | 1/20 | 0.43 |
| ▸ | PYGL | P06737 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001577 | 1.00 | SLC5A2 (0.44) | SLC5A2MAPTCDAPYGLPTPN1 | |
| SCHEMBL6789608 | 0.82 | MAPT (0.43) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6791272 | 0.82 | MAPT (0.43) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6789071 | 0.82 | PYGL (0.45) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6791266 | 0.82 | MAPT (0.43) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6790626 | 0.82 | PYGL (0.45) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6791561 | 0.82 | MAPT (0.43) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6784647 | 0.78 | MAPT (0.40) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL6784652 | 0.78 | MAPT (0.40) | SLC5A2MAPTCDAPYGL | |
| SCHEMBL8177221 | 0.77 | SMN1; SMN2 (0.47) | SLC5A2MAPTCDAPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3903392-B2 | — | — | 2007-04-11 | — | — | JP | claimed |
| US-6248878-B1 | INCLUDING BASES 2-FLUOROPYRIDINE-3-YL, PYRIDINE-2-ONE-3-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-3-YL, 2-BROMOPYRIDINE-5-YL , PYRIDIN-2-ONE-5-YL, 2-AMINOPYRIDINE-5-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-5-YL; ANTISENSE/ANTICANCER AGENTS | RIBOZYME PHARMACEUTICALS, INC. | 2001-06-19 | — | — | US | claimed |
| JP-2001507688-A | — | — | 2001-06-12 | — | — | JP | claimed |
| EP-0948511-A2 | CHEMICAL SYNTHESIS OF NUCLEOSIDES ANALOGS AND THEIR INCORPORATION INTO POLYNUCLEOTIDES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1999-10-13 | — | — | EP | claimed |
| WO-1998028317-A2 | SYNTHESIS OF NUCLEOSIDES AND POLYNUCLEOTIDES | RIBOZYME PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | claimed |
| US-6248878-B1 | INCLUDING BASES 2-FLUOROPYRIDINE-3-YL, PYRIDINE-2-ONE-3-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-3-YL, 2-BROMOPYRIDINE-5-YL , PYRIDIN-2-ONE-5-YL, 2-AMINOPYRIDINE-5-YL, PYRIDIN-2-(4-NITROPHENYLETHYL)-ONE-5-YL; ANTISENSE/ANTICANCER AGENTS | RIBOZYME PHARMACEUTICALS, INC. | 2001-06-19 | — | — | US | disclosed |