Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7914995 | 0.87 | ATM (0.43) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL32679864 | 0.84 | ATM (0.58) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL10343404 | 0.83 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL30869991 | 0.83 | ATM (0.70) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL12271110 | 0.83 | ATM (0.56) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL19229231 | 0.81 | ATM (0.54) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL23913120 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31556190 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL31556187 | 0.81 | ATM (0.68) | ATMKDM4ECA2POLBCYP19A1 | |
| SCHEMBL5488875 | 0.81 | KMT2A (0.46) | MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985577-A | POLYSILAZANES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | claimed |
| JP-2009888-A | — | — | None | — | — | JP | disclosed |
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |
| US-4985577-A | POLYSILAZANES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4985577-A | POLYSILAZANES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| US-4985577-A | POLYSILAZANES | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| JP-H029888-A | 3-(3,4-DIMETHOXYPHENYL)PROPYLTRICHLOROSILANE | SHIN ETSU CHEM CO LTD | 1990-01-12 | — | — | JP | disclosed |