SCHEMBL5488875

SCHEMBL5488875

COc1ccc(CCCCCCCCCCC[Si](Cl)(Cl)Cl)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
ALDH1A1 P00352 1/20 0.46
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42
TUBB8 Q3ZCM7 1/20 0.42
TUBA3E Q6PEY2 1/20 0.42
TUBA1A Q71U36 1/20 0.42
TUBA1C Q9BQE3 1/20 0.42
TUBB6 Q9BUF5 1/20 0.42
TUBB2B Q9BVA1 1/20 0.42
TUBB1 Q9H4B7 1/20 0.42
TTR P02766 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1003949 0.81 MEN1 (0.48) KMT2AMEN1ALDH1A1TUBB4ATUBB
SCHEMBL15022597 0.81 MEN1 (0.48) KMT2AMEN1ALDH1A1TUBB4ATUBB
SCHEMBL5486749 0.81 ATM (0.56) KMT2AMAPT
SCHEMBL13241453 0.79 SMN1; SMN2 (0.56) KMT2AMEN1ALDH1A1TTRSMN1; SMN2
SCHEMBL26641603 0.78 TNKS2 (0.51) KMT2AMEN1ALDH1A1TUBB4ATUBB
SCHEMBL6348746 0.78 KDM4E (0.56) KMT2AMEN1ALDH1A1TTRSMN1; SMN2
SCHEMBL5485255 0.76 CALM1 (0.53) SMN1; SMN2
SCHEMBL8060167 0.75 MEN1 (0.54) KMT2AMEN1ALDH1A1TTRSMN1; SMN2
SCHEMBL14144999 0.74 POLB (0.53) KMT2AMEN1ALDH1A1TTRSMN1; SMN2
SCHEMBL22010379 0.74 SELP (0.54) HSD17B10SMN1; SMN2MAPK1PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7291747-B2 Silicon compounds and process for preparation thereof CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20040143081-A1 Novel silicon compounds and process for preparation thereof JNC CORPORATION (JP) 2004-07-22 US disclosed