Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MB | P02144 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480287 | 0.80 | CHRM2 (0.49) | SMN1; SMN2MAPTHTTMEN1KMT2A | |
| SCHEMBL5478145 | 0.78 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL5478476 | 0.77 | HTR6 (0.35) | SMN1; SMN2MAPTHTTMEN1CYP3A4 | |
| SCHEMBL5482126 | 0.75 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTNPC1RAB9ALRRK2 | |
| SCHEMBL5488536 | 0.74 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTLRRK2HTTALDH1A1 | |
| SCHEMBL5478939 | 0.72 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL5483441 | 0.71 | SMN1; SMN2 (0.52) | SMN1; SMN2MAPTHTTALDH1A1MEN1 | |
| SCHEMBL5474337 | 0.70 | SMN1; SMN2 (0.60) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL5479179 | 0.70 | SMN1; SMN2 (0.53) | SMN1; SMN2MAPTNPC1RAB9AHTT | |
| SCHEMBL5485863 | 0.69 | HTT (0.67) | SMN1; SMN2MAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | TOPO TARGET A/S (DK) | 2007-12-27 | — | — | US | claimed |
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | TOPO TARGET A/S (DK) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299102-A1 | Diphenyl Ox-Indol-2-One Compounds and Their Use in the Treatment of Cancer | MTOR, RICTOR, CDK4 | SMN1; SMN2 234/4885MAPT 1785/4885NPC1 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.