Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928462 | 0.90 | MEN1 (0.57) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5423738 | 0.89 | PTGDR2 (0.54) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5412989 | 0.87 | MAPT (0.51) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL5354225 | 0.87 | MAPT (0.57) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5392676 | 0.84 | MAPT (0.48) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4916217 | 0.79 | MAPT (0.63) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL14184689 | 0.79 | MAPT (0.66) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5421225 | 0.78 | GAA (0.49) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL4926481 | 0.77 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5367089 | 0.77 | GAA (0.62) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |