SCHEMBL548691

SCHEMBL548691

O=Cc1cccc(-c2cccc(C=O)c2C=O)c1C=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
LMNA P02545 2/20 0.52
THRB P10828 1/20 0.52
BLM P54132 1/20 0.52
ERN1 O75460 4/20 0.44
ALDH1A1 P00352 4/20 0.44
TRIM24 O15164 2/20 0.42
TRIM33 Q9UPN9 2/20 0.42
TSHR P16473 1/20 0.42
CYP2A6 P11509 1/20 0.39
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TLR2 O60603 1/20 0.38
TLR1 Q15399 1/20 0.38
TLR6 Q9Y2C9 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547759 0.93 KMT2A (0.52) KMT2AMEN1TDP1LMNATHRB
SCHEMBL547829 0.86 KMT2A (0.61) KMT2AMEN1TDP1LMNATHRB
SCHEMBL29639996 0.85 KMT2A (0.44) KMT2AMEN1TDP1LMNATHRB
SCHEMBL28476269 0.85 KMT2A (0.44) KMT2AMEN1TDP1LMNATHRB
SCHEMBL5116358 0.85 TDP1 (0.39) KMT2AMEN1TDP1LMNATHRB
SCHEMBL17422064 0.85 KMT2A (0.44) KMT2AMEN1TDP1LMNATHRB
SCHEMBL28880001 0.85 TRIM24 (0.57) KMT2AMEN1TDP1LMNATHRB
SCHEMBL549020 0.84 KMT2A (0.48) KMT2AMEN1TDP1LMNATHRB
SCHEMBL29390160 0.84 KMT2A (0.48) KMT2AMEN1TDP1LMNATHRB
SCHEMBL548517 0.84 ERN1 (0.38) KMT2AMEN1TDP1LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115960343-B High-activity oligomer catalyst and method for preparing alkylene oxide and cyclic anhydride alternating copolymer by using same 大连理工大学 2024-04-02 CN claimed
CN-115960343-A High-activity oligomer catalyst and method for preparing alkylene oxide and cyclic anhydride alternating copolymer by using same 大连理工大学 2023-04-14 CN claimed
CN-108117642-B Synthesis method of three-dimensional adamantane organic framework porous material 中国科学院大连化学物理研究所 2020-11-20 CN claimed
CN-108117642-A A kind of synthetic method of three-dimensional adamantane organic frame porous material 中国科学院大连化学物理研究所 2018-06-05 CN claimed
CN-108117641-A A kind of method that three-dimensional covalent organic frame material is synthesized using ionic liquid 中国科学院大连化学物理研究所 2018-06-05 CN claimed
CN-106396736-A Method for growing three-dimensional covalent organic frame material on surface of alpha-Al2O3 ceramic 中国科学院大连化学物理研究所 2017-02-15 CN claimed
CN-1276027-C Composite polyamide/clay material and its prepn and use CHINESE ACAD INST CHEMISTRY (CN) 2006-09-20 CN claimed
CN-1609143-A Composite polyamide/clay material and its prepn and use CHINESE ACAD INST CHEMISTRY (CN) 2005-04-27 CN claimed
US-12427506-B1 Method for carbon dioxide fixation using a palladium-doped nitrogen-rich organic framework catalyst KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2025-09-30 US disclosed
US-12071503-B2 Method for preparing and repairing covalent organic framework materials ZHEJIANG UNIVERSITY (CN) 2024-08-27 US disclosed
CN-115960343-B High-activity oligomer catalyst and method for preparing alkylene oxide and cyclic anhydride alternating copolymer by using same 大连理工大学 2024-04-02 CN disclosed
CN-115960343-A High-activity oligomer catalyst and method for preparing alkylene oxide and cyclic anhydride alternating copolymer by using same 大连理工大学 2023-04-14 CN disclosed
US-11542397-B2 Liquid composition, quantum dot-containing film, optical film, light-emitting display element panel, and light-emitting display device TOKYO OHKA KOGYO CO., LTD. (JP) 2023-01-03 US disclosed
US-20220153904-A1 A METHOD FOR PREPARING AND REPAIRING COVALENT ORGANIC FRAMEWORK MATERIALS ZHEJIANG UNIVERSITY (CN) 2022-05-19 US disclosed
US-4116945-A ELECTRICAL CONDUCTING PHTHALONITRILE POLYMERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-09-26 US disclosed
US-4116945-A ELECTRICAL CONDUCTING PHTHALONITRILE POLYMERS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-09-26 US disclosed
US-4102873-A SEMICONDUCTORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-07-25 US disclosed
US-4102873-A SEMICONDUCTORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1978-07-25 US disclosed
US-4057569-A SEMICONDUCTORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-11-08 US disclosed
US-4057569-A SEMICONDUCTORS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1977-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12427506-B1 Method for carbon dioxide fixation using a palladium-doped nitrogen-rich organic framework catalyst POF1B, CYP4F12, ETFB KMT2A 2319/4885MEN1 3131/4885TDP1 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.