Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 8/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 4/20 | 0.57 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26885220 | 0.84 | DEGS1 (0.79) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL2467402 | 0.84 | PLAU (0.78) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL1232738 | 0.83 | CA12 (0.74) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL1232739 | 0.83 | CA12 (0.74) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL7890716 | 0.83 | DEGS1 (1.00) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL3656661 | 0.83 | DEGS1 (0.77) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL29518660 | 0.83 | DEGS1 (1.00) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL12658950 | 0.82 | CA12 (0.69) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL1232918 | 0.82 | CA12 (0.69) | DEGS1NPC1RAB9ACASP3SENP7 | |
| SCHEMBL16316028 | 0.82 | NPC1 (0.59) | NPC1RAB9AKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1845083-A2 | New arylsulfonohydrazide inhibitors of enzymes MurC and MurD | UNIVERZA V LJUBLJANI, FAKULTETA ZA FARMACIJO (SI) | 2007-10-17 | — | — | EP | disclosed |