Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 5/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13041518 | 0.84 | TAAR1 (0.42) | XIAPBIRC2TAAR1 | |
| SCHEMBL5487725 | 0.84 | TAAR1 (0.42) | XIAPBIRC2TAAR1 | |
| SCHEMBL8317295 | 0.83 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL2959039 | 0.83 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL13041333 | 0.82 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL2961130 | 0.82 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL13265592 | 0.82 | SLC6A3 (0.32) | SLC6A3 | |
| SCHEMBL2955111 | 0.81 | PSEN1 (0.38) | SLC6A3 | |
| SCHEMBL12966143 | 0.81 | PSEN1 (0.38) | SLC6A3 | |
| SCHEMBL8320230 | 0.81 | PSEN1 (0.38) | SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511267-A1 | 3-((N-ACYLATED AMINOACYL)AMINO)PYRAZOLES AS INHIBITORS OF BETA-AMYLOID PEPTIDE PRODUCTION USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE | Elan Pharmaceuticals Inc. (US) | 2012-10-17 | — | — | EP | claimed |
| US-20070197624-A1 | Acylated amino acid amidyl pyrazoles and related compounds | ELAN PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197624-A1 | Acylated amino acid amidyl pyrazoles and related compounds | APP, BACE1, APH1A | SLC6A3 1749/4885XIAP 3372/4885BIRC2 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.