SCHEMBL5487235

SCHEMBL5487235

Cc1cc(CNCC(=O)N(C)Cc2nc(-c3ccc(Cl)cc3)oc2C)cc(C)c1OC(C)(C)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 17/20 0.54
PPARG P37231 16/20 0.54
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5475387 0.93 PPARA (0.46) PPARAPPARGTP53MAPTHSD17B10
SCHEMBL5485451 0.91 PPARA (0.54) PPARAPPARGTP53MAPT
SCHEMBL5487230 0.86 PPARA (0.61) PPARAPPARGHSD17B10
SCHEMBL5487237 0.85 PPARA (0.49) PPARAPPARGTP53MAPTHSD17B10
SCHEMBL5482138 0.84 PPARA (0.47) PPARAPPARGTP53MAPT
SCHEMBL5487241 0.80 PPARA (0.62) PPARAPPARG
SCHEMBL5475390 0.80 PPARA (0.51) PPARAPPARGTP53MAPTHSD17B10
SCHEMBL5477324 0.80 PPARA (0.75) PPARAPPARG
SCHEMBL5487225 0.79 PPARA (0.51) PPARAPPARGTP53MAPTHSD17B10
SCHEMBL5479552 0.78 PPARA (0.64) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885TP53 1596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.